Autoimmune myocarditis: a clinical entity. |
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Authors: | L. N. Dragatakis, J. Klassen, I. Hü ttner, D. G. Fraser, N. L. Poirier, G. A. Klassen |
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Affiliation: | L. N. Dragatakis, J. Klassen, I. Hüttner, D. G. Fraser, N. L. Poirier, and G. A. Klassen |
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Abstract: | In a case of myocarditis electron microscopic and immunoflourescent studies of a transmural myocardial biopsy specimen indicated an autoimmune process. Extensive inflammatory cell infiltration, immunoglobulin and complement deposition along the sarcolemma and in the interstitium, and capillary endothelial injury were found. After a short course of immunosuppressive therapy the inflammatory process was replaced by collagenous scarring and lymphocytic depletion; the blood vessels were then normal. Earlier therapy in such cases may be lifesaving. |
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