Ⅰ期子宫内膜癌不同术式疗效的研究

目的　对Ⅰ期子宫内膜癌不同术式的疗效及其术后并发症进行比较分析。方法　回顾性分析 1986年 1月至 1997年 12月手术治疗的 2 11例Ⅰ期子宫内膜癌 ,根据术式不同分为两组 ,61例采用全子宫加双侧附件切除术 (组 1) ,150例采用广泛性全子宫切除术 (组 2 )。对两组的疗效及术后并发症进行比较分析。结果　组 1和组 2总的 5年生存率分别为 96 0 %、93 5% ,两组比较 ,差异无显著性 (P >0 0 5) ;复发率分别为 6 6%、10 7% ,两组比较 ,差异无显著性 (P >0 0 5) ;术后并发症分别为 11 5%、2 4 7% ,两组比较 ,差异有显著性 (P <0 0 5)。结论　Ⅰ期子宫内膜癌患者可以采用全子宫加双侧附件切除术

Study of different surgeries for clinical stage I endometrial carcinoma

OBJECTIVE: To compare the outcomes and the risk of post-operative complications in patients with stage I endometrial carcinoma who were treated with different surgeries. METHODS: A total of 211 cases with stage I endometrial cancer treated with surgery in our Cancer Center from Jan 1986 to Dec 1997 were analyzed retrospectively. Sixty-one patients (group 1) underwent simple hysterectomy and salpingo-oophorectomy and 150 patients (group 2) underwent radical hysterectomy. The 5-year survival rates and the risk of post-operative complications were compared between two groups. RESULTS: Five-year survival rates of the group 1 and 2 were 96.0% and 93.5% (P > 0.05), respectively. The recurrence rates of the two groups were 6.6% and 10.7% (P > 0.05), respectively. The overall rates of post-operative complications in the two groups were 11.5% and 24.7% (P < 0.05), respectively. CONCLUSION: The patients with stage I endometrial carcinoma who were treated with simple hysterectomy and salpingo-oophorectomy did almost as well as those who underwent radical hysterectomy.