| 脑出血患者血浆中ET—1,SP含量变化及临床意义 |
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| 引用本文： | 许二赫,许一多.脑出血患者血浆中ET—1,SP含量变化及临床意义[J].中风与神经疾病杂志,1998,15(5):283-284. |
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| 作者姓名： | 许二赫 许一多 |
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| 作者单位： | 白求恩医科大学二院神经内科，白求恩医科大学三院综合内科 |
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| 摘 要： | 目的动态观察３０例脑出血患者血浆内皮素－１（ＥＴ－１）、Ｐ物质（ＳＰ）含量变化。方法应用放射免疫分析法（ＲＩＡ）。结果（１）急性期血浆ＥＴ－１、ＳＰ含量显著高于对照组。（２）急性期血浆ＥＴ－１、ＳＰ含量显著高于恢复期。（３）急性期血浆ＥＴ－１含量与ＳＰ含量呈正相关。结论ＥＴ－１、ＳＰ共同参与和影响脑出血的病理生理过程，血浆ＥＴ－１、ＳＰ含量的增高在一定程度上反映了脑出血的严重程度
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| 关 键 词： | 内皮素 P物质 脑出血 |
The changes of plasma ET and SP on patients with cerebral hemorrhage and its clinical significance |
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| Xu Erhe,Xu Yiduo,Hu Guohua.The changes of plasma ET and SP on patients with cerebral hemorrhage and its clinical significance[J].Journal of Apoplexy and Nervous Diseases,1998,15(5):283-284. |
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| Authors: | Xu Erhe Xu Yiduo Hu Guohua |
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| Institution: | Xu Erhe,Xu Yiduo,Hu Guohua.Department of Neurology,The Second Clinical College of Norman Bathune University,Changchun 130041 |
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| Abstract: | Objective We have studied the plasma ET and SP levels in 30 patients of cerebral hemorrhage (CH) and have made a dynamic observation in the patients.Method RIA is applied in the study.Results (1)The levels of plasma ET 1 and SP were increased in acute stage of CH as compared with controls.(2)The levels of plasma ET 1 were increased in acute stage of CH as compared with recovery stage of CH.The levels of SP were increased in acute stage of CH as compared with recovery stage of CH.(3)The concentration of plasma ET in acute stage of CH was positively correlated with that of SP.Conclusions ET and SP are involved in pathophysiologic course of CH.The increase of plasma ET and SP suggest the varias degree of CH. |
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| Keywords: | Endothelium Substance P Cerebral hemorrhage |
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