肝移植术后患者下呼吸道细菌分布及耐药性

目的：研究肌移植术后患者下呼吸道感染的细菌分布及耐药情况。方法：对182例肝移植术后并发下呼吸道感染患者的病原菌进行分析，统计其检测结果及药敏结果。结果：病原菌总检出率为75.4％，革兰阴性菌占60.8％．革兰阳性菌占28．9％，真菌占10．3％，主要致病菌依次为大肠埃希菌、肺炎克雷伯菌、金黄色葡萄球菌和铜绿假单胞菌等。对大多数抗菌药物耐药。结论：肝移植术后患者下呼吸道感染的细菌种类及其对临床常用的抗菌药物耐药率增加。合理、适当选用抗菌药物对降低肝移植患者术后感染非常重要。

The Bacterial Distribution and Antibiotic Resistance of Lower Respiratory Tract Infections in Liver Transplantation Patients

Objective: To investigate the bacterial distribution and antibiotic resistance of lower respiratory tract infections in liver transplantation patients. Methods: Retrospective investigation from the lower respiratory tract bacterial infections of 182 liver transplant patients and the drug-sensitivity results were analyzed. Results: The total percentage of the detected pathogens was 75.4% ,of all these strains,60.8% was Gram-negative bacteria,28.9% was Gram-positive bacteria and 10.3% was fungi.The main bacteria were Escherichia coil?Klebsiella pneumoniae?Staphylococcus aureusand Pseudomonas aeruginosa,and the majority was drug-resistant. Conclusion: Types of pathogens of lower respiratory tract bacterial infections in liver transplantation as well as their antibiotic resistance increase , it is very important to decrease the postoperative infection of the liver transplantation by using antibiotics rationally and properly.