Yucatan Pig: An Optimal Hairless Model for a True Random Cutaneous Flap |
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Authors: | Louis DeLuca Michael Beckenstein Bahman Guyuron |
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Institution: | (1) Cleveland, Ohio, USA, US |
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Abstract: | Porcine models have been used extensively for skin flap research because of the established similarity between the cutaneous
blood supply of the swine and humans. The Yucatan minipig provides an excellent model for researching the properties of random
cutaneous flaps, offering several advantages over other breeds of swine. In this study, a total of 67 random cutaneous dorsal
flank flaps measuring 4 × 14 cm were raised on nine Yucatan minipigs. The mean survival length (10.03 ± 1.60 cm) of the nondelayed
flaps was greater than others reported in the literature. The well-defined plane between the subcutaneous tissue and the panniculus
carnosus facilitated flap elevation consistently above the level of the panniculus carnosus thereby ensuring the creation
of a true random cutaneous flap. Furthermore, the hairless nature of the skin, particularly beneficial in studying chemical
peels, permits easy visualization and monitoring of any external skin changes. These advantages make the Yucatan minipig a
more desirable alternative to other breeds of swine for use in skin flap research. |
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Keywords: | : Random cutaneous flaps— Skin flap research— Chemical peel studies |
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