乳腺癌TIC Ⅱ、Ⅲ型曲线类型及ADC值与Ki-67相关性研究 |
| |
引用本文: | 赵茹,赵红,邹立巍,郑穗生. 乳腺癌TIC Ⅱ、Ⅲ型曲线类型及ADC值与Ki-67相关性研究[J]. 安徽医科大学学报, 2015, 0(2): 220-223 |
| |
作者姓名: | 赵茹 赵红 邹立巍 郑穗生 |
| |
作者单位: | 安徽医科大学第二附属医院放射科,合肥,230601;安徽医科大学第二附属医院放射科,合肥,230601;安徽医科大学第二附属医院放射科,合肥,230601;安徽医科大学第二附属医院放射科,合肥,230601 |
| |
基金项目: | 安徽省高等学院省级自然科学基金 |
| |
摘 要: | 目的:探讨乳腺癌MRI动态增强曲线( TIC)类型、弥散表观系数( ADC)值与免疫组化标志物Ki-67表达的相关性。方法搜集乳腺病例43例,全部行MRI动态增强扫描及弥散加权成像( DWI),测其TIC类型及其ADC值,且所有病例做病理和肿瘤指标Ki-67的免疫组化,并统计分析TICⅡ、Ⅲ型曲线类型及ADC值与Ki-67的表达是否存在相关性。结果乳腺癌ADC值越低,其Ki-67表达越高; TIC曲线类型Ⅲ型者Ki-67表达较Ⅱ型者阳性率高。结论 TIC类型及ADC值与Ki-67的表达存在一定相关性,可为临床评估乳腺癌预后提供有利依据。
|
关 键 词: | 乳腺癌 ADC值 TIC曲线 Ki-67 |
Correlations between Ki-67 and the TIC curve type and the ADC values of patients in breast cancer |
| |
Affiliation: | Zhao Ru;Zhao Hong;Zou Liwei;Dept of Radiology,The Second Affiliated Hospital of Anhui Medical University; |
| |
Abstract: | Objective The aim of this study was to determine the relationships among Ki-67 and the TIC curve type and the ADC values of patients in breast cancer. Methods 43 patients who performed dynamic contrast-enhanced MRI and diffusion weighted imaging( DWI) in preoperative phase were selected. Measuring ADC values and dy-namic enhancement curve ( TIC) type. And all of these patients had done the pathology and the tumor marker of Ki-67 . Statistical analysis was used to compare the correlations between Ki-67 and the TIC type and the ADC values. Results The lower the ADC valued, the higher the Ki-67expressed. The Ki-67 expressions in TIC curve type Ⅲ were higher than type Ⅱ. Conclusion The dynamic enhanced MRI curve type and the ADC values have a certain correlation with the expressions of Ki-67 , and can provide advantageous basis for clinical to assess the prognosis of breast cancer. |
| |
Keywords: | breast cancer ADC TIC curve type Ki-67 |
本文献已被 CNKI 万方数据 等数据库收录! |