| 关于CRRT滤器清除率计算公式的验证和讨论 |
| |
| 引用本文： | 罗洁伟,田莉艳,颜林,柯军,徐苏华.关于CRRT滤器清除率计算公式的验证和讨论[J].中国医疗器械信息,2021(7):15-17,178. |
| |
| 作者姓名： | 罗洁伟 田莉艳 颜林 柯军 徐苏华 |
| |
| 作者单位： | 广东省医疗器械质量监督检验所 |
| |
| 基金项目： | 广州开发区科技创新局项目(项目名称:高性能血液灌流器的临床应用与产业化研究,项目编号:201802010019);广州市科技项目(项目名称:广州市生物医用血液净化材料研究与开发重点实验室,项目编号:穗科信字[2013]163-5号)。 |
| |
| 摘 要： | 目的:验证一种更适用CRRT滤器产品清除率计算的公式。方法:按产品使用说明书设置血液流速、透析液流速和超滤率,分别测定尿素、肌酐、磷酸氢二钾和维生素B12四种物质在血液出入口和透析液出口的浓度,用YY 0053-2016《血液透析及相关治疗血液透析器、血液透析滤过器、血液滤过器和血液浓缩器》公式(使用血液侧浓度)和需验证的公式(使用透析液侧浓度)计算产品的清除率。结果:连续性血液透析使用血液侧浓度计算的清除率偏差明显高于使用透析液侧浓度计算的清除率偏差。结论:对于CRRT滤器来说,使用透析液侧浓度的公式进行清除率的计算偏差更小,更加准确。
|
| 关 键 词： | CRRT 滤器 清除率计算公式 血液侧 透析液侧 |
Verification and Discussion of the Formula for Calculating the Clearance of CRRT Haemodiafilters |
| |
| LUO Jie-wei,TIAN Li-yan,YAN Lin,KE Jun,XU Su-hua.Verification and Discussion of the Formula for Calculating the Clearance of CRRT Haemodiafilters[J].China Medical Devices Information,2021(7):15-17,178. |
| |
| Authors: | LUO Jie-wei TIAN Li-yan YAN Lin KE Jun XU Su-hua |
| |
| Institution: | (Guangdong Medical Devices Quality Surveillance and Inspection Institute/NMPA Key Laboratory of Extracorporeal Circulation Devices/Guangzhou Biomedical Blood Purification Materials Research and Development Key Laboratory,Guangdong Guangzhou 510663) |
| |
| Abstract: | Objective:To verify a clearance calculation formula which is more applicable to CRRT haemodiafilters.Method:Set up the blood flow rate,dialysate flow rate,ultrafiltration rate as shown in the product instruction,Measure the concentration of the urea,creatinine,dipotassium phosphate and vitamin B12 both on the blood and dialysate inlet/outlet side.Caculate the clearance of the CRRT haemodiafilters by using both the formula in YY 0053-2016 Hemodialysis and revlevant therapies-Haemodialysers,haemodiafilters,haemofilters and haemoconcentrators,which using the concentration of the blood-side,and the formula to be verified,which using the concentration of the dialysate-side.Result:The deviation of the clearance calculated by the formula using the concentration of the blood-side is significantly higher than that when using the concentration of the dialysate-side.Conclusion:The clearance calculation formula using the concentration of the dialysate-side is more applicable to CRRT haemodiafilters. |
| |
| Keywords: | CRRT haemodiafilters clearance calculation formula the blood-side the dialysate-side |
| 本文献已被 维普 等数据库收录！ |
|
