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Avian-origin H3N2 canine influenza A viruses in Southern China
Authors:Shoujun Li  Zhihai Shi  Peirong Jiao  Guihong Zhang  Zhiwen Zhong  Wenru Tian  Li-Ping Long  Zhipeng Cai  Xingquan Zhu  Ming Liao  Xiu-Feng Wan
Institution:1. College of Veterinary Medicine, South China Agricultural University, Guangzhou, China;2. Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA;1. Jiangsu Engineering Laboratory of Animal Immunology, Institute of Immunology and College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China;2. Animal Infectious Disease Laboratory, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China;3. Key Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University, Hangzhou 310058, China;4. CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China;5. CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China;6. Collaborative Innovation Center and State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University, Hangzhou 310003, China;7. Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, Jiangsu, 225009, China;8. Jiangsu Research Centre of Engineering and Technology for Prevention and Control of Poultry Disease, Yangzhou, Jiangsu, 225009, China;9. National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention (China CDC), Beijing, China;1. State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing 100193, China;2. College of Veterinary Medicine, China Agricultural University, Beijing 100193, China;3. Key Laboratory of Animal Disease Control and Prevention of the Ministry of Agriculture, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China;1. College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi 330045, China;2. Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA;3. Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;4. Jiangxi Provincial Center for Animal Disease Control and Prevention, Nanchang, Jiangxi 300006, China;5. College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong 510642, China;6. CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, China Academy of Sciences, Beijing 100190, China;7. Office of Director-General, Chinese Center for Disease Control and Prevention (China CDC), Beijing 102206, China;8. Institute for Genomics, Biocomputing and Biotechnology, Mississippi State University, Mississippi State, MS 39762, USA;1. Department of Biological and Agricultural Engineering, University of Arkansas, Fayetteville, AR 72701, USA;2. Cell and Molecular Biology Program, University of Arkansas, Fayetteville, AR 72701, USA;3. Department of Poultry Science, Center of Excellence for Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA;4. Animal Diagnostic Laboratory, Pennsylvania State University, State College, PA 16802, USA;5. College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China
Abstract:This study reports four sporadic cases of H3N2 canine influenza in Southern China, which were identified from sick dogs from May 2006 to October 2007. The evolutionary analysis showed that all eight segments of these four viruses are avian-origin and phylogenetically close to the H3N2 canine influenza viruses reported earlier in South Korea. Systematic surveillance is required to monitor the disease and evolutionary behavior of this virus in canine populations in China.
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