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精准肝切除在结直肠癌肝转移中的临床应用研究
引用本文:张健,彭勇,田云鸿,胡韬,马海,杜天祥,杨红春.精准肝切除在结直肠癌肝转移中的临床应用研究[J].川北医学院学报,2014,29(2):133-136.
作者姓名:张健  彭勇  田云鸿  胡韬  马海  杜天祥  杨红春
作者单位:张健 (南充市中心医院·川北医学院附属第二临床学院,肝胆胰外科,四川南充637000); 彭勇 (南充市中心医院·川北医学院附属第二临床学院,肝胆胰外科,四川南充637000); 田云鸿 (南充市中心医院·川北医学院附属第二临床学院,肝胆胰外科,四川南充637000); 胡韬 (南充市中心医院·川北医学院附属第二临床学院,肝胆胰外科,四川南充637000); 马海 (南充市中心医院·川北医学院附属第二临床学院,肝胆胰外科,四川南充637000); 杜天祥 (南充市中心医院·川北医学院附属第二临床学院,肝胆胰外科,四川南充637000); 杨红春 (南充市中心医院·川北医学院附属第二临床学院,肝胆胰外科,四川南充637000);
基金项目:四川省教育厅青年基金项目(项目编号:12ZB042)
摘    要:目的:探讨精准肝脏切除术在结直肠癌肝转移中的治疗效果。方法:回顾分析我院2007年6月至2013年5月结直肠癌肝转移的肝脏切除病例,23例行精准肝切除,31例采用传统Pringle法肝门阻断的肝切除术,在手术时间、术中出血、术后肝功能恢复、住院时间等多方面做对比。结果:精准肝切除组与Pringle法肝切除组比较,手术时间延长,(325.3±41.8)vs(264±31.1)]min,P<0.05;术中出血量减少(357±91.4)vs(577±75.2)]mL,P<0.05;术后肝脏功能恢复加快,ALT:(343.5±114.4)vs(704.3±142.8)]U/L、AST:(430.7±140.0)vs(704.3±142.8)]U/L、TBIL:(35.5±12.1)vs(62.8±18.1)]μmol/L,P均<0.05;住院时间缩短(17.6±3.2)vs(25.8±2.1)]d,P<0.05。结论:精准肝切除术相比传统肝脏切除术,术中出血少,肝脏功能恢复快,住院时间短。

关 键 词:精准肝切除  结直肠癌  肝转移

Clinical application reasearch of precise colorectal cancer hepatectomy in liver metastasis of
ZHANG Jian,PENG Yong,TIAN Yun-hong,HU Tao,MA Hai,DU Tian-xiang,YANG Hong-chun.Clinical application reasearch of precise colorectal cancer hepatectomy in liver metastasis of[J].Journal of North Sichuan Medical College,2014,29(2):133-136.
Authors:ZHANG Jian  PENG Yong  TIAN Yun-hong  HU Tao  MA Hai  DU Tian-xiang  YANG Hong-chun
Institution:( Hepatopancreatobiliary Surgery Department, Nanchong Central Hospital, The Second Clinical Hospital of North Sichuan Medical Col lege , Nanchong 637000, Sichuan, China )
Abstract:Objective:To Study the cure effects of precise hepatectomy in liver metastasis of colorectal cancer. Methods: Retrospec tively analyze patients with liver metastasis of co]orectal cancer with hepatectomy from June 2007 to May 2013.23 cases underwent pre cise hepatectomy ;31 cases underwent the traditional pringle hepatectomy of hepatic portal occlusion. The surgery time,blood loss,post operative liver function recovery, hospital stays etc. were compared. Results : Conpared with the patients in pringle maneuver hepatecto my group, the operative time was longer in precise hepatectomy group ( 325.3 ± 41.8 ) vs ( 264 ± 31. 1 ) ] min, P 〈 0. 05 ; but the patients in precise hepatectomy group had less blood loss ( 357 ± 91.4) vs ( 577± 75.2) ] mL, P 〈 0.05 ; Liver function recovered more rapidly after operation ALT(343.5 ± 114. 4)U/L vs(704.3± 142. 8) U/L;AST(430.7 ± 140. 0)U/L vs(704. 3 ±142. 8) U/L;TBIL(35.5 ± 12.1 )umol/L vs(62.8 ± 18.1 ) μmol/L ] , P 〈 0.05. Conclusion:Compared with the traditional hepatectomy, the precise hepatectomy has less blood loss, more rapid recoveny of the liver function and less time in the hospital
Keywords:Precise hepatectomy  Colorectal cancer  Liver metastasis
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