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血管内介入治疗颈内动脉眼动脉段动脉瘤的临床效果分析
引用本文:徐剑峰,谢晓东,王朝华,张昌伟,张紫寅,范锋,胡利刚,徐丁,向守卫.血管内介入治疗颈内动脉眼动脉段动脉瘤的临床效果分析[J].成都医学院学报,2014,9(1):18-21.
作者姓名:徐剑峰  谢晓东  王朝华  张昌伟  张紫寅  范锋  胡利刚  徐丁  向守卫
作者单位:徐剑峰 (四川大学华西医院神经外科,成都,610041); 谢晓东 (四川大学华西医院神经外科,成都,610041); 王朝华 (四川大学华西医院神经外科,成都,610041); 张昌伟 (四川大学华西医院神经外科,成都,610041); 张紫寅 (四川大学华西医院神经外科,成都,610041); 范锋 (四川大学华西医院神经外科,成都,610041); 胡利刚 (四川大学华西医院神经外科,成都,610041); 徐丁 (四川大学华西医院神经外科,成都,610041); 向守卫 (四川大学华西医院神经外科,成都,610041);
基金项目:四川省科技厅支撑项目(项目编号:2012SZ0127)
摘    要:目的探讨血管内介入治疗在颈内动脉段眼动脉段动脉瘤的应用与临床效果分析。方法同顾性分析2006年1月~2013年1月本院神经外科实施的血管内介入治疗颈内动脉眼动脉段动脉瘤114例患者的临床资料。其中,男性51例,女性63例;年龄〈40岁者21例,40~60岁者42例,≥60岁者51例,平均(53.4±4.1)岁。结果本组共查见129枚动脉瘤(89枚行支架辅助弹簧圈栓塞术,40枚例行单纯弹簧圈栓塞术)。随访12个月发现:动脉瘤完全闭塞、大部闭塞者、小部分闭塞者分别为109枚、12枚、8枚。x2检验结果显示:支架辅助弹簧圈栓塞治疗组闭塞效果(91.0%VS70%;x2=9.356,P=0.009)及改良Rankin量表(modified rankins cale,mRS)评分(89.3%VS80.2%;x2=5.632,P=0.021)分别明显优于单纯弹簧圈栓塞治疗组。结论颈内动脉眼动脉段动脉瘤血管内介入治疗安全、有效,支架辅助弹簧圈栓塞治疗瘤体闭塞方面效果较好,能显著改善患者预后,值得推广。

关 键 词:介入  血管内治疗  颈内动脉  眼动脉段动脉瘤

Analysis of Clinical Effects of Intravascular lnterventional Treatment for Ophthalmic Segment Aneurysms of the Internal Carotid Artery
Authors:XU Jian-feng  XIE Xiao-dong  WANG Chao-hua  ZHANG Ckang-wei  ZHANG Zi yin  FAN Feng  HU Li-gang  XU Ding  XIANG Shou-wei
Institution:(Department of Neurosurgery, West Ckina Hospital, Sichuan University, Chengdu 610041, Ckina)
Abstract:Objective To investigate the clinical results of ophthalmic segment aneurysms of the internal carotid artery by intravascular interventional treatments. Methods Collected the clinical data of 114 patients who were admitted to this hospital for ophthalmic segment aneurysms of the internal carotid artery during January 2006 to January 2013, and retrospectively analyzed. There were 51 cases of male and 63 cases of female. The average age was (53.4±4.1) years old, of which younger than 40, 40-60, and elder than 60 years were 21 cases,42 cases, and 51 cases, respectively. Results A total of 129 aneurysms were detected by DSA. Of these, 89 cases received treatment with stents assisted coil embolizations, and 40 cases received treatment with coil embolization exclusively. The results of follow-up for 12 months showed that 109 cases were densely embolized, 12 cases were sub-totally embolized, 8 cases were partially embolized. Results of the Pearson Chi square test showed that enterprise stent treatment were significantly better for embolization effects (91. 0% VS 70% ; x2 =9.356, P=0. 009) and modified Rankin scales (89.3 % VS 80.2 % ; x2 = 5. 632, P = 0. 021) than the coil embolization alone. Conclusion The coil embolization treatment of ophthalmic segment aneurysms of internal carotid artery, assisted by stent, can be densely embolized. It is effective and safe, resulting in a better prognosis. This tent-assisted treatment is worth promoting.
Keywords:Interventional  Intravaseular Treatment  Internal Carotid Artery  Ophthalmic Segment Aneurysms
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