重型颅脑损伤并发多器官功能障碍的预后分析

目的:探讨重型颅脑损伤并发多器官功能障碍的预后特点。方法:总结我科2008年3月至2013年3月收治的547例重型颅脑损伤并发多器官功能障碍患者的预后。结果:重型颅脑损伤并发多器官功能障碍死亡率较高,达36.7%;GCS评分越低则死亡率越高(P<0.05);GCS≥5分时合并脏器功能障碍数量越多死亡率越高(P<0.05);GCS<5分时合并不同数量脏器功能障碍死亡率无明显差异(P>0.05)。结论:重型颅脑损伤并发器官障碍的数量及GCS评分与死亡率有相关性。早期预防、早期治疗可能出现的多器官功能障碍,对降低重型颅脑损伤的死亡率有重要的意义。

The prognostic analysis of severe crania-cerebral injury complicating mul tiple organ dysfunction

Objective：Explore and discuss the prognostic features of severe crania-cerebral injury complicating multiple organ dys function. Methods：To summarize the prognostic features of 547 severe crania-cerebral injury complicating multiple organ dysfunction cases, which were hospitalized in our department from March 2008 to March 2013. Results：Severe crania-cerebral injury complicating multiple organ dysfunction has higher mortality,which is 36.7% ;the patients with lower GCS are higher in mortality（ P 〈 0.05 ） ;if GCS ≥ 5, the patients with more organ dysfunction are higher in mortality （P 〈 0.05 ） ;but if GCS 〈 5, the patients with different amount of organ dysfunction have no manifest discrepancy of mortality（P 〉 0.05 ）. Conclusion ：The amount of organ dysfunction and GCS score of severe crania-cerebral injury complicating organ dysfunction is associated with mortality. It has considerable significance for reducing mortality of severe crania-cerebral injury with early precaution and treatment for multiple organ dysfunction.