预注氯诺昔康用于腹腔镜阑尾切除术后镇痛

目的 观察预注氯诺昔康对腹腔镜阑尾切除术后疼痛的影响.方法 ASA级Ⅰ～Ⅱ行腹腔镜阑尾切除术的患者80例,随机分为实验组和对照组,每组40例.麻醉前实验组静注氯诺昔康16 mg,对照组静注生理盐水4 ml.采用腰硬联合麻醉,术中静注哌替啶、氟哌利多和咪唑安定维持镇静.术后4、8、12、24 h对患者用视觉模拟评分法(V...

Preempty analgesic effect of lornoxican on postoperstive analgesia in patients undergoing laparoscopic appendectomy

Objective To investigate the effect of pretreatment with lornoxicam on postoperative analgesia in patients undergoing laparoscopic appendectomy. Methods Eighty patients undergoing laparoscopic appendectomy were randomly assigned to receive intravenous lornoxicam of 16 mg (40patients,study group ) or normal saline of 4 ml (40 patients,control group ) before anesthesia. All the patients were anesthetized with combined spinal epidural blockage and tranquilized with pethedine,droperidol and midazolan. Postoperative pain was assessed by visual analogue scale(VAS )and Bruggman Comfort Scale (BCS ). Adverse reactions were noted. Results The VAS scores were lower in the study group than in the control group at hours 2,8,12,and 24(1.5 ± 0.6 vs. 4.9 t 0.9,2.1 ± 0.8 vs. 5.6 ±0.8,2.0 ± 0.7 vs. 5.5 ± 0.9,and 1.9 ± 1.0 vs. 5.4 ± 1.1; P＜0.05 ) and the BCS scores were higher in the study group than in the control group (3.9 ± 0.7 vs. 1.2 ± 0.8,3.2 ± 0.8 vs. 0.9 ± 0.6,3.5±0.9 vs. 0.9 ± 0.5,and 2.8 ± 1.1 vs. 0.6 ± 0.8 P＜0.05 ; while the number of supplemental analgesic use decreased in the study group (4 vs. 10,P＜0.05 ) Conclusions Pretreatment with lornoxicam for patients undergoing laparoscopic appendectomy can relieve postoperative pain while reducing the use of supplemental analgesics.