下咽及颈段食管鳞癌的治疗

目的：研究下咽及颈段食管鳞癌的治疗效果。方法：回顾性分析117例初治下咽及颈段食管鳞癌不同治疗方法的效果。结果：总3年生存率为60．0％，术前放疗原发灶达到完全缓解与非完全缓解者3年生存率分别为82.0%、45.0%。术后发生并发症27例（23．1％）。死亡47例，其中局部复发未控15例（31．9％），颈部复发未控11例（23．4％），远处转移6例（12．8％）。术前放疗喉功能保留率为46．3％，而单纯手术或术后放疗者为27．3％。结论：术前放疗为主的综合治疗可提高下咽颈段食管鳞癌的生存率及喉功能的保留率；术前放疗完全缓解者生存率较高。局部复发与颈部淋巴结转移是下咽颈段食管癌的主要死亡原因。

Treatment for Squamous Cell Carcinoma in Hypopharynx and Cervical Esophagus

Purpose To evaluate the result of treatment for hypopharyngeal and cervical esophageal carcinoma.One hundred and seventeen cases with squamous cell carcinoma of hypopharynx and cervical esophagus who were treated with different methods were reviewed.The overall survival rate of 3 years was 60.0%.Complete remission and incomplete remission following preoperative radiotherapy were 82.0% and 45.0% respectively.In dead cases,the rate of local recurrence was 31.9%(15/47);neck failure,23.4%(11/47), distant metastasis, 12.8%(6/47).The rate of laryngeal preservation with preoperative radiotherapy was 46.3%;no preoperative radiotherapy,27.3%.Conclusion]Preoperative radiotherapy combined with sugery is an effective strategy to promote survival rate and achieve organ preservation in patients with squamous cell carcinoma of hypopharynx and cervical esophagus.