三种不同药物治疗抑郁症病人的成本-效果分析

目的 :评价 3种不同药物治疗抑郁症的经济效果。 方法 :对 115例抑郁症病人随机分组 ,分别用 3种不同的药物治疗 ,A组用氯米帕明 ,B组用氟西汀 ,C组用吗氯贝胺。运用药物经济学的最小成本分析及成本 效果分析方法比较。 结果 :3种方案的疗效无显著性差异 (P >0 .0 5 ) ,B方案不良反应发生率最低、成本 效果比最低。 结论 :药物经济学在优化治疗方案、指导合理用药、减轻病人经济负担方面具有重要意义。

Cost-effectiveness analysis of three drugs in treatment of patients with depression

Objective: To evaluate the economic effectiveness of three different drugs for treatment of patients with depression. Methods: One hundred and fifteen patients with depression were randomly divided into 3 groups. They received different therapeutic regimens, A: clomipramine, B: fluoxetine, C: moclobemide. Results: There was no significant difference in effectiveness among three different therapeutic regimens (P>0.05). The incidence of adverse drug reaction of regimen B was the lowest and the cost-effectiveness ratio of this regimen was the lowest too. Conclusion: Pharmacoeconomics plays an important role in optimizing therapeutic regimen, guiding rational use of drugs and lightening the expense of patients.