精神心理干预联合HCG治疗未破裂卵泡黄素化综合征的临床疗效观察

目的探讨精神心理干预联合人绒毛膜促性腺激素（Humanchorionicgonadotropin，HCG）治疗未破裂卵泡黄素化综合征（LuteinizedUnrupturedFollicleSyndrome，LUFS）的临床疗效。方法将40例LUFS门诊患者随机分为治疗组与对照组各20例，两组均用HGG注射治疗，治疗组加以精神心理干预。观察比较两组患者焦虑自评量表（SAS）得分、黄体生成素（Luteinizinghormone，LH）、总排卯率等指标差异。结果治疗组治疗前后SAS和SDS评分差异均有统计学意义（P〈0．05），对照组治疗前后SAS和SDS评分差异无统计学意义（P〉0．05）；HCG注射当天两组LH水平差异有统计学意义（P〈0．05），E2及P水平差异无统计学意义（P〉0．05）；治疗组总排卵率85．00％，明显高于对照组的55．00％（P〈0．05）；治疗组排卵后一周血E2、P水平均高于对照组（P〉0．05）。结论采用精神心理干预联合HCG治疗LUFS，在改善患者的心理状况的同时，还可提高LH值，提高排卵率。

The clinical effects of psychological intervention combined HCG in the treatment of LUFS

Objective To investigate the clinical efficacy of psychological intervention combined human chorionic gonadotropin （HCG） in the treatment of luteinized unruptured follicle syndrome （LUFS）. Methods 40 cases of LUFS patients were selected and randomly divided into the experimental group and the control group of our study. The experimental group received relaxation therapy, supportive therapy and other psychological interventions, in addition to HGG injection therapy, while the control group were treated with HGG injection. Both groups were compared for differences in each index. Findings The difference in SAS and SDS scores of the experimental group before and after treatment was statistically significant （ P 〈 0.05 ）. The control group showed no significant difference （ P 〉 0.05 ） ： LH levels difference ofthe two groups was statistically significant in HCG injection day （ P 〈 0. 05） , E2 and P levels showed no significant difference （P 〉 0.05 ） ; The experimental group＇s ovulation rate was 85.00% , which was much higher than that of the control group, where the total ovulation rate was 55.00% （P 〈0.05 ） ; Blood E2, P levels of treatment group one week after ovulation were higher （P ~, 0.05 ）. Conclusion The combination of psychological intervention in human chorionic gonadotropin （HCG） treatment of luteinized unruptured follicle syndrome （LUFS） could improve the patient＇s mental state, promote hormone secretion, and increase ovulation rate.