| 小剂量尿激酶治疗频发短暂性脑缺血发作临床研究 |
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| 引用本文： | 刘树国,鲍晓玲,孙志宝. 小剂量尿激酶治疗频发短暂性脑缺血发作临床研究[J]. 泰山医学院学报, 2006, 27(4): 328-329 |
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| 作者姓名： | 刘树国 鲍晓玲 孙志宝 |
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| 作者单位： | 1. 滨州职业学院中专部,山东,滨州,256609
2. 滨州市人民医院,山东,滨州,256610 |
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| 摘 要： | 目的 研究小剂量尿激酶对频发的短暂性脑缺血发作（TIA）的疗效。方法 将64例频发的TIA患者随机分为治疗组和对照组。治疗组在对照组治疗的基础上加用小剂置尿激酶静脉点滴，连续5．7d。结果 治疗组治疗后24h内及72h内TIA发作控制率分别是71．9％和93．8％，均高于对照组18．8％和50％（P〈0．01）；且治疗组血浆粘度和纤维蛋白原较对照组明显降低（IP〈0．01）。结论 小剂量尿激酶治疗频发TIA疗效显著、安全、见效快，且能有效防止脑梗死的发生。
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| 关 键 词： | 尿激酶 治疗 短暂性脑缺血发作 |
| 文章编号： | 1004-7115（2006）04-0328-02 |
| 收稿时间： | 2006-05-10 |
| 修稿时间： | 2006-05-10 |
A clinical study of small-dose urokinase in the treatment of frequent transient ischemic attack |
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| LIU Shuguo ,BAO Xiaoling. A clinical study of small-dose urokinase in the treatment of frequent transient ischemic attack[J]. Journal of Taishan Medical College, 2006, 27(4): 328-329 |
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| Authors: | LIU Shuguo BAO Xiaoling |
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| Affiliation: | I. Binzhou Vocational College, Shandong 256609. Sun Zhibao ;2. Binzhou People Hospital, Shandong 256610 China |
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| Abstract: | Objective:To study the clinical effect of small-dose urokinase in the treatment of frequent transient ischemic attack(TIA).Methods:Sixty-four patients with TIA were randomly divided into study group and control group.The study group added small-dose urokinase to ivdrip for 5-7 days in the base of the treatment of the control group.Results:The control rates to attack of the study group were respectively 71.9% and 93.8% within twenty-four hours and seventy-two hours after treatment,they were higher than 18.8% and 50% of the control group(P<0.01);and the fibrinogen and serous mucosity of the study group were significantly lower than the control group(P<0.01).Conclusion:Small-dose urokinase is effective and safe in the treatment of frequent TIA,and it can effectively prevent cerebtral infarction. |
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| Keywords: | Urokinase treatment Transient ischemic attack |
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