Surgical approach to early familial medullary carcinoma of the thyroid gland |
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| Authors: | H H Miller K E Melvin J M Gibson A H Tashjian |
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| Affiliation: | 1. From the Surgical Tumor Service, Department of Surgery, Tufts University School of Medicine and The New England Medical Center Hospitals, Boston, Massachusetts USA;2. From the Endocrinology Service, Department of Medicine, Tufts University School of Medicine and The New England Medical Center Hospitals, Boston, Massachusetts USA;3. From the Department of Pathology, Tufts University School of Medicine and The New England Medical Center Hospitals, Boston, Massachusetts USA;4. From the Pharmacology Department, Harvard School of Dental Medicine and Department of Pharmacology, Harvard Medical School, Boston, Massachusetts USA |
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| Abstract: | The application of a radioimmunoassay for human calcitonin to a high risk family group has predicted the diagnosis of medullary carcinoma of the thyroid in twelve persons. With the calcium infusion test, elevated levels of calcitonin have been measured in the serum and urine in these patients with medullary carcinoma. In eleven, the tumors were clinically occult. |
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