102例女性泌尿系感染临床分析

目的探讨女性泌尿系感染(UTI)的临床特点,以提高临床诊断、治疗水平。方法收集2003年1月-2006年12月102例女性UTI的病例进行检索,对其发病特点、感染部位、合并全身疾病状况、致病菌分布、治疗效果等进行回顾性分析。结果102例UTI患者,上尿路感染57例(55.90%),下尿路感染45例(44.1%);复杂性尿路感染85例(83.30%),非复杂性尿路感染17例(16.7%);合并全身疾病依次为泌尿系结石、泌尿系肿瘤、糖尿病,慢性肾实质病变,性传播疾病等。致病菌中革兰阴性菌(64.3%),其中又以大肠埃希菌为主(40.5%),革兰阳性菌(31%),其中又以屎肠球菌为主(17.9%)。治疗总有效率为87.3%。结论女性UTI以上尿路感染且合并全身疾病者居多,致病菌多为革兰阴性菌,提示临床医师诊断时注重感染部位鉴别、致病菌分布以针对性选择抗生素,及时治疗合并的全身性疾病。

Clinical Analysis of 102 Female Patients with Urinary Tract Infection

Objective To analyze the clinical features of female patients with urinary tract infection(UTI) for the improvement of the clinical diagnosis and treatment.Method 102 female hospitalized patients with UTI in this hospital between Jan.2003 and Dec.2006 were studied retrospectively.The clinical features,the distribution of the pathogens,and the clinical outcome of the treatment were analyzed.Result 57 cases were upper UTI(55.90%),45 cases were lower UTI(44.1%),85 cases were complicated UTI(83.30%),and 17 cases were non-complicated UTI(16.7%).The complications were urinary stones,urologic neoplasms,diabetes,chronic renal parenchyma disease,and sexually transmitted diseases(STDs).64.3% of isolates were Gram-negative bacteria.Escherichia coli,accounting for 40.24% of the isolates,was the predominant pathogen.31% of the isolates were Gram-positive bacteria,and Enterococcus faecium(17.9%) was the predominant pathogens.87.3% of patients were successfully treated.Conclusion Most of the female patients with UTI had both upper UTI and other diseases.The major bacterial isolates were Gram-negative bacteria.Attention should be made in the identification of site of infection,the distribution of pathogens,and the selection of antibiotics for the treatment of infection.