| 胰岛素上调3T3-L1细胞apelin基因表达的初步观察 |
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| 引用本文： | 魏丽,侯兴华,贾伟平.胰岛素上调3T3-L1细胞apelin基因表达的初步观察[J].中华内分泌代谢杂志,2006,22(4):384-385. |
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| 作者姓名： | 魏丽 侯兴华 贾伟平 |
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| 作者单位： | 200233,上海交通大学附属上海市第六人民医院内分泌代谢科 |
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| 摘 要： | Northern印迹法证实apelin在分离的小鼠脂肪细胞上有表达，其表达量随3T3-L1细胞分化而渐增。胰岛素上调3T3-L1脂肪细胞apelin的表达，提示脂肪细胞apelin的表达可能与肥胖、胰岛素抵抗、高血压相关。
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| 关 键 词： | Apelin 脂细胞 3T3-L1细胞 胰岛素 |
| 收稿时间： | 2005-07-04 |
| 修稿时间： | 2005年7月4日 |
Insulin up-regulates expression of apelin gene in 3T3-L1 cells: a preliminary observation |
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| WEI Li,HOU Xing-hua,JIA Wei-ping.Insulin up-regulates expression of apelin gene in 3T3-L1 cells: a preliminary observation[J].Chinese Journal of Endocrinology and Metabolism,2006,22(4):384-385. |
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| Authors: | WEI Li HOU Xing-hua JIA Wei-ping |
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| Abstract: | Expression of apelin mRNA in the isolated mouse adipocytes was confirmed by Northern blot. The level of apelin mRNA increased during stage of differentiation of 3T3-L1 cells. Insulin up-regulated the apelin expression in 3T3-L1 adipocytes, suggesting that apelin expression in adipocyte may correlate with obesity, insulin resistance and hypertension. |
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| Keywords: | Apelin Adipocytes 3T3-L1 cell Insulin |
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