阿托伐他汀治疗高脂血症50例临床观察

目的：观察阿托伐他汀治疗高脂血症的临床效果。方法：选择50例总胆固醇（TC）≥6.5 mmol/L或甘油三酯（TG）≥1.7 mmol/L或高密度脂蛋白胆固醇（HDL-C）≤1.30 mmol/L患者,给予阿托伐他汀10 mg,每天1次,晚间顿服,于用药8周后分别测定血脂四项、血常规、肝肾功能、谷丙转氨酶（ALT）、肌酸磷酸激酶（CK）等。结果：治疗前后血脂有显著变化,改善血TC、TG、HDL-C的总有效率分别为96.0%、72.0%、70.0%。未发现明显不良反应。结论：阿托伐他汀治疗高脂血症效果显著,副作用小,对预防心血管疾病有实际意义。

50 Cases with Hyperlipidemia Treated by Atorvastatin

Objective：To observe the effect of treatment of hyperlipidemia with atorvastatin.Methods：50 patients with total cholesterol（TC）≥6.5 mmol/L or triglyceride（TG）≥1.7 mmol/L or high-density lipoprotein cholesterol（HDL-C） ≤1.30 mmol/L were selected.Atorvastatin 10mg were given,day 1.At 8 weeks,the four lipids、blood、liver and kidney function,alanine aminotransferase（ALT）,creatine kinase（CK） were measured.Results：Before and after treatment significant changes in blood lipids.total effective rate of improving blood TC,TG,LDL-C,HDL-C was 96.0%,72.0%,70.0% respectively.No significant adverse drug reactions were found.Conclusion：The effect of atorvastatin be treated for hyperlipidemia is significant,less side effects,it＇s meaningful for preventing cardiovascular daisease.