Hepatoprotective potential of petroleum ether leaf extract of Crossandra infundibuliformis on CCl4 induced liver toxicity in albino mice

ObjectiveTo analyze the hepatoprotective effect of the Crossandra infundibuliformis.MethodsHepatotoxicity was induced by carbon tetrachloride. Petroleum ether extract of dried leaves was administrated to mice for 7 days. The hepatoprotective effect of petroleum ether extract was evaluated by the assay of liver function biochemical parameters.ResultsThe result clearly indicates that petroleum ether extract showed significant hepatoprotection when compared with standard Silumarin.ConclusionsThe petroleum ether extract of the leaves of Crossandra infundibuliformis possess significant acute hepatoprotective activity. Thus further investigation on this species would bring a promising drug for liver disorders.