平均递增率在心血管病理流行病学中的应用

本文应用平均递增率数列，并结合检出率数列，对７１５９例冠状动脉（冠脉）尸检病理资料进行再分析。结果表明：从动脉粥样硬化（ＡＳ）的形成到发生冠脉狭窄大约需要２０～３０年。如何把握这段时间并进行适宜的干预，对预防冠心病具有重要意义。所有的人在一生中或早或晚都会发生ＡＳ，但只有不足二分之一的人会发生冠脉狭窄，其原因值得深入研究。

APPLICATION OF AVERAGE INCREASING RATE IN CARDIOVASCULAR PATHOLOGICAL EPIDEMIOLOGY

In this paper,a set of epidemiological data of atherosclerotic(As) lesions and stenosis in coronary arteries from 7159 cases of human autopsy was reanalyzed for longitudinal implication by evaluating both the prevalence rate and its average annual increasing rate.The results showed that about 20-30 years is needed from the appearance of As lesion to the manifestation of stenosis.So it is of great importance to prevent the progression of As lesion to stenosis as well as coronary heart disease during this long period.Furthermore almost all of the 7 159 cases had coronary As,but only<50% of them developed coronary stenosis and the cause of which remains to be elucidated.