复发性口腔鳞癌挽救性手术近期疗效

目的　探讨不同期复发性口腔鳞癌挽救性手术治疗的疗效。方法　对 30例首次复发的复发性口腔鳞癌患者临床再分期后行挽救性手术并跟踪随访。结果　复发性口腔鳞癌早期患者的总生存时间及无瘤生存时间均比复发进展期者长 ,且复发早期 1年生存率及 1年无瘤生存率均高于复发进展期。结论　对复发性口腔鳞癌进行临床的再分期有利于评价预后及制定治疗方案 ;挽救性手术是复发性口腔鳞癌的有效治疗手段 ,尤其对复发性口腔鳞癌早期的患者

Effect of salvage surgery for patients with recurrent oral squamous cell carcinoma

Objective To examine the benefit of restaging recurrent oral squamous cell carcinoma(R OSCC) and the effect on salvage surgery Methods An analysis was performed on 30 patients with local only first failure ( n =13) or loca regional only first failure ( n =9) or first recurrence in the neck ( n =8) after surgery and/or radiation treatment given for oral squamous cell carcinoma. All the 30 patients were restaged and treated with salvage surgery Results The overall survival time and disease free survival time of patients with early staged R OSCC was longer than that of patients with advanced staged R OSCC. The 1 year survival and 1 year disease free survival rates for early staged R OSCC is also higher than that of advanced staged R OSCC. Conclusions The re stage of the recurrent tumor is significantly correlated with survival.The salvage surgery is an effective ineasure in patients with recurrent oral squamous cell carcinoma, especially in early staged patients of R OSCC