原发性小肠淋巴瘤临床病理分析23例

Clinicopathological features of primary small intestinal lymphoma: analysis of 23 cases

AIM: To summarize the clinicopathologic features of the small intestinal lymphoma. METHODS: The clinical data, including the initial symptoms or signs, involved locations, histological subtypes, and complications, of 23 patients pathologically diagnosed with small intestinal lymphoma were retrospectively analyzed. RESULTS: The initial symptoms or signs included abdominal pain (13 cases, 56.5%), abdominal mass (6 cases, 26.1%), melena or hematochezia (2 cases, 8.7%), diarrhea (1 cases, 4.3%), and constipation (1 cases, 4.3%). Five patients had B-symptom. The involved locations were ileocecum (7 cases, 30.4%), jejunum (7 cases, 30.4%), ileum (6 cases, 26.1%), and duodenum (1 cases, 4.3%). Multiple involvements appeared in 2 cases (8.7%). Hodgkin's lymphoma was not found in all the patients. Of the 23 cases, 19 were B-cell origin (82.6%) and 4 were T-cell origin (17.4%). For histological subtypes, 13 cases (56.5%) were diagnosed with diffuse large B cell lymphoma, 6 cases (26.1%) with B-cell MALT lymphoma, 3 cases (13.0%) with diffuse T-cell lymphoma, and 1 cases (4.3%) with enteropathy-associated T cell lymphoma. CONCLUSION: Abdominal pain is the most common symptom for small intestinal lymphoma, and the most frequently involved location is ileocecum and jejunum. B-cell origin covers a larger percent. Diffuse large B cell non-Hodgkin's lymphoma is commonly occurred in terms of histological classification.