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Clinical and psychosocial factors associated with fatigue in patients with Parkinson's disease
Authors:Havlikova Eva  Rosenberger Jaroslav  Nagyova Iveta  Middel Berrie  Dubayova Tatiana  Gdovinova Zuzana  W Groothoff Johan  P van Dijk Jitse
Affiliation:

aDepartment of Neurology, Faculty of Medicine, University PJ Safarik, Trieda SNP 1, 040 01 Kosice, Slovakia

bInstitute of Social Sciences and Kosice Institute for Society and Health, University PJ Safarik, Kosice, Slovakia

cDepartment of Care Sciences, University Medical Center Groningen, University of Groningen, The Netherlands

dDepartment of Social Medicine, University Medical Center Groningen, University of Groningen, The Netherlands

Abstract:Fatigue is an important contributor to poor quality of life. The aim of our research was to identify factors associated with fatigue among patients with Parkinson's disease (PD). The sample consisted of 150 patients. The Multidimensional Fatigue Inventory (MFI), Unified Parkinson's Disease Rating Scale (UPDRS), Hospital Anxiety and Depression Scale (HADS) and Charlson co-morbidity index were used for analysis. Demographic data were obtained in a structured interview. T-test, χ2-test and general linear regression were used. Fatigue was reported in 81% of the patients, with the worst scores in physical fatigue. Mood disorders and worse UPDRS scores were associated with fatigue.
Keywords:Fatigue   Parkinson's disease   Depression   Anxiety   Co-morbidity
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