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复方枣仁水提物对小鼠学习记忆的影响研究
引用本文:陈红燕,刘思源,袁丽娟,张天监,李诗,覃媛.复方枣仁水提物对小鼠学习记忆的影响研究[J].中国药业,2011,20(16):29-31.
作者姓名:陈红燕  刘思源  袁丽娟  张天监  李诗  覃媛
作者单位:中国人民解放军第44医院药剂科,贵州,贵阳,550009
摘    要:目的观察复方枣仁水提物对小鼠学习记忆能力的影响。方法采用跳台法观察复方枣仁水提物对记忆获得障碍小鼠、记忆巩固障碍小鼠和正常小鼠学习记忆能力的影响。结果复方枣仁水提物可明显减少记忆获得障碍小鼠在跳台中错误次数(P<0.01)和明显延长潜伏期(P<0.05),可明显减少记忆巩固障碍小鼠错误次数(P<0.05)和明显延长潜伏期(P<0.05)。结论复方枣仁可显著改善小鼠学习记忆能力。

关 键 词:复方枣仁  学习记忆  记忆获得障碍  记忆巩固障碍

Research on Impact of Compound Zaoren Aqueous Extract to Learning and Memory in Mice
Chen Hongyan,Liu Siyuan,Yuan Lijuan,Zhang Tianjian,Li Shi,Qin Yuan.Research on Impact of Compound Zaoren Aqueous Extract to Learning and Memory in Mice[J].China Pharmaceuticals,2011,20(16):29-31.
Authors:Chen Hongyan  Liu Siyuan  Yuan Lijuan  Zhang Tianjian  Li Shi  Qin Yuan
Institution:Chen Hongyan,Liu Siyuan,Yuan Lijuan,Zhang Tianjian,Li Shi,Qin Yuan(Department of Pharmacy,44 Hospital of PLA,Guiyang,Guizhou,China 550009)
Abstract:Objective To observe the impact of compound Zaoren aqueous extract to the learning and memory ability in mice.Methods Using the step-down test,the effects of compound Zaoren aqueous extract to the learning and memory ability in the memory acquirement disorder mice,the memory consolidation disorder mice and the normal mice were observed.Results Compound Zaoren water extract could significantly reduce the number of errors of the diving platform(P < 0.01) and significantly prolonged the latency period in the m...
Keywords:compound Zaoren  learning and memory  memory acquirement disorder  memory consolidation disorder  
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