住院的慢性乙型肝炎患者生活质量及其影响因素研究

目的：调查住院慢性乙型肝炎患者生活质量及其影响因素。方法：住院慢性乙型肝炎患者、来本院体检的正常人以及肝炎专科门诊的慢性ＨＢＶ感染者各７６名均使用ＳＦ－３６生活质量量表进行调查。住院患者同时使用心理控制源量表、应对方式量表、社会支持量表、抑郁量表和焦虑量表进行调查。结果除生理机能领域外，慢性乙型肝炎患者生活质量的其它领域均低于正常人群（Ｐ〈０．０５），多数领域亦明显低于门诊患者；患者的抑郁和焦虑情绪与生活质量的各领域均有明显负相关，自现及幻想、陷瞒等应对方式及机遇性心理控制源与患者生活质量的精神健康领域有明显负相关。结论：慢性乙型肝炎对生活质量的各领域均有影响；心理社会因素是影响患者生活质量的主要因素。

A Study on Quality of Life of Chronic Hepatitis B Inpatients and Its Related Factors

Objective: To investigate the quality of life of chronic hepatitis B inpatients and its relevant contributing factors. Methods: The SF-36 quality of life questionnaire was administrated to 76 chronic hepatitis B inpatients, 76 chronic hepatitis B outpatients and 76 normal controls. Additional measures including Zung's Self-rating Anxiety Scale, Zung's Self-rating Depression Scale, Wallston's Multidimensional Health Locus of Control Scale, Vitaliano's Coping Checklist, and Social Support Scale were administrated to the chronic hepatitis B inpaitents. Results: The quality of life of chronic hepatitis B inpatients was reduced when compared with normal controls and outpatients of chronic hepatitis B in most of the domains assessed. The scores of anxiety and depression were found to be negatively correlated with scores of quality of life for all domains. The scores of self-blame and imagination, the hide the fact coping styles, and opportunistic locus of control were negatively correlated with scores on the mental health domain of quality of life. Conclusion: The quality of life of chronic hepatitis B inpatients was significantly reduced as compared to normal controls and outpatients. Psychosocial factors constitute the major determinants for quality of life.