Risk of recurrence after treatment of early breast cancer with skin-sparing mastectomy |
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Authors: | Dr Stephen S Kroll MD Mark A Schusterman MD Helen E Tadjalli MD S Eva Singletary MD Frederick C Ames MD |
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Institution: | (1) From the Departments of Plastic Surgery and Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA |
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Abstract: | Background: Skin-sparing mastectomy, combined with immediate breast reconstruction, has become increasingly popular. However, there are
no published long-term data to support its oncologic safety. Our purpose was to evaluate the long-term oncologic risk of skin-sparing
mastectomy.
Methods: The records of all patients who had undergone treatment of T1 or T2 breast cancer by mastectomy and immediate breast reconstruction,
and who were followed for at least 5 years or developed recurrence of disease before that time were reviewed. Local and distant
recurrence rates observed in patients treated by skin-sparing mastectomy were compared with those in patients treated by conventional,
non-skin-sparing mastectomy.
Results: A total of 104 patients were treated with skin-sparing mastectomies. In that group, 6.7% developed local recurrences, 12.5%
developed distant metastases, 88.5% remained free of disease, and 7.7% died of their disease. Among the 27 patients who did
not have skin-sparing mastectomies, 7.4% had local recurrences, 25.9% had distant metastases, 74.1% remained free of disease,
and 18.5% died of disease. These recurrence rates are similar to those reported elsewhere after treatment with conventional
mastectomy and without reconstruction.
Conclusions: Our findings suggest that skin-sparing mastectomy does not significantly increase the risk of local or systemic disease recurrence
in patients with early breast cancer. |
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Keywords: | Breast cancer Skin-sparing mastectomy |
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