| 调节性T细胞在炎症性肠病中的研究进展 |
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| 引用本文： | 何相宜,陈维雄.调节性T细胞在炎症性肠病中的研究进展[J].世界华人消化杂志,2007,15(28):3015-3019. |
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| 作者姓名： | 何相宜 陈维雄 |
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| 作者单位： | 上海交通大学附属第六人民医院消化内科,上海市,200233 |
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| 摘 要： | 炎症性肠病(IBD)是一种非特异性肠道炎症性疾病,其发病与自身免疫功能紊乱有关.Th1/Th2失衡是导致IBD的重要因素之一.然而,Th1/Th2理论并不能充分阐明IBD的发病机制.近几年来,越来越多的研究显示,调节性T细胞在炎症性肠病的发生发展中起重要的作用.本文就近年来调节性T细胞在炎症性肠病中作用的研究进展作一综述.
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| 关 键 词： | 炎症性肠病 调节性T细胞 自身免疫 |
| 收稿时间： | 2007-06-14 |
| 修稿时间： | 2007-09-24 |
Progress in research the roles of regulatory T cells in inflammatory bowel disease |
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| Xiang-Yi He,Wei-Xiong Chen.Progress in research the roles of regulatory T cells in inflammatory bowel disease[J].World Chinese Journal of Digestology,2007,15(28):3015-3019. |
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| Authors: | Xiang-Yi He Wei-Xiong Chen |
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| Abstract: | Inflammatory bowel disease(IBD)is a nonspecific intestinal inflammatory disease.Its causes and pathogenesis have a close relationship with disorder of autoimmune function.The imbalance of the Th1/Th2 paradigm is an important factor for IBD.However,the pathogenesis of IBD cannot be interpreted on the basis of the Th1/Th2 paradigm alone.Recent research has highlighted the substantial role of regulatory T cells in the nosogenesis of IBD.This review will explore the relationship between regulatory T cells and IBD,and the progress in the study of regulatory T cells. |
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| Keywords: | Inflammatory bowel disease Regulatory T cell Autoimmunity |
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