两种皮肤消毒液对青霉素皮试结果的影响

目的 观察0．5％碘伏与75％乙醇两种皮肤消毒方法对青霉素皮试结果的影响。方法 选择2004年6月-2006年6月内科住院患者500例，分组间对照组（n=250）及自身对照组（n=250）进行研究。观察0．5％碘伏和75％乙醇两种皮肤消毒液作青霉素皮试后出现的假阳性率。结果 组间对照组及自身对照组青霉素皮试假阳性率。75％乙醇消毒分别为10．8％和12％；0．5％碘伏消毒均为0．8％（P〈0．05）。结论 0．5％碘伏替代75％乙醇作青霉素皮试消毒液可减少青霉素皮试假阳性反应的发生，有助于更好地判断皮试结果。

Effect of Two Different Disinfectant in Penicillion Skin Tests

Objective To observe the effect of two different disinfectant(0.5% iodophor and 75% alcohol) in penicillion skin test.Methods Five hundred patients were randomly divided into two groups,contrast group(n=250) and self contrast group(n=250).False positive rate of penicillion skin tests was observed after disinfection with 0.5% iodophor and 75% alcohol.Results 0.5% iodophor decreased the false positive rate resulting from 75 % alcohol significantly(P<0.05).Conclusion 0.5 % iodophor should be the effective disinfectant to be used to substitute 75% alcohol in penicillin skin test.