健康老年人脑容量的计算机辅助CT面积测量

目的为了解健康老龄脑生理性改变，并为痴呆患者脑萎缩提供诊断依据，寻找敏感、实用的反映脑容量的测量方法。方法收集８１名健康老年人的颅脑ＣＴ片，将它们放在摄像头下方，图像输入计算机后定好标尺即可用鼠标器划定被测面积，再输入计算机，得出具体数值。结果脑实质指数、第三脑室面积、鞍上池指数、干池比例、外侧裂指数和侧脑室指数的增龄性变化均有统计学意义（Ｐ＜０．０５）。结论健康老年人脑容量有明显的增龄性变化，包括幕下的小脑。脑室指标的变化比脑实质的变化更敏感，可作为重点检测的指标。

The computerassisted area measurement of the brain volume on CT films in healthy aged individuals

Objective To understand the physiological changes of healthy aging brain,to supply the diagnosetic basis for the patients with dementia and to detect a practicable measuring method that can sensitively reflect the changes of the brain volume. Method We collected 81 brain CT films of the healthy elderly persons,put the brain CT films under the camera,input the pictures in the screen of the computer, set the size of the gauge and delimited the area of being measured with mouse. Results The area changes of the brain substances and the third ventricles were significant statistically (P<0. 05). The changes of the indexes of supra sellar cisternfissures of sylvius and the lateral ventricles and the proportion of the brain stem to pon cistern were all significant statistically(P<0.05). Conclusion There were obvious aged changes of the brain volumes including the cerebellum in healthy aged individuals.The changes of the ventricular areas, except the fouth ventricle, were more sensitive than those of the brain substances. It was suggestted that the indexes of the ventricular might serve as the more important observational indexes in the healthy aged individuals.