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Heparinization during percutaneous cardiac catheterization in children
Authors:Dr. Heinrich Netz  Bertram Madu  Gottfried Röhner
Affiliation:(1) Department of Paediatric Cardiology, Justus-Liebig University, Giessen, Germany;(2) Kinderkardiologie, Zentrum für Kinderheilkunde, Feulgenstr. 12, D-63 Giessen, Germany
Abstract:Summary The effect of heparin on blood clotting was studied by measuring the activated clotting time (ACT) in 120 infants and children with congenital heart disease after a single intravenous bolus of 100 IU heparin/kg body weight. Before heparinization, infants and children with cyanotic heart disease showed signs of hypocoagulation. Heparin bolus led to a threefold increase of ACT after 15 min. After 1 h, the ACT was still two times the normal value. Any further administration of heparin may be based on ACT monitoring.Dedicated to Prof. H. W. Rautenburg.
Keywords:Heparinization  Cardiac catheterization  Congenital heart disease  Activated clotting time  Blood clotting
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