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Peribulbar anaesthesia using a mixture of local anaesthetic and vecuronium
Authors:G. Reah,A. R. Bodenham,P. Braithwaite,J. Esmond,&   M. J. Menage
Affiliation:Senior Registrar, Department of Anaesthesia, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK,;Consultant Anaesthetist, Department of Anaesthesia, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK,;Consultant Anaesthetist, Department of Anaesthesia, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK,;Specialist Registrar, Department of Anaesthesia, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK,;Consultant Ophthalmologist, Department of Ophthalmology, The General Infirmary at Leeds, Great George Street, Leeds LS1 3EX, UK
Abstract:The aim of this double-blind, randomised study was to assess the effects of the addition of 0.5 mg of vecuronium bromide to a standard local anaesthetic mixture used for peribulbar anaesthesia. We studied 60 patients undergoing regional anaesthesia for intra-ocular surgery and were primarily interested in the quality of globe and lid akinesia. All received a mixture of 5 ml 2% lignocaine with 1:200 000 adrenaline, 5 ml 0.75% bupivacaine and 150 IU hyaluronidase with either 0.9% saline 0.25 ml (group A, n  = 30) or vecuronium bromide 0.25 ml (0.5 mg) (group B, n  = 30). Eye movements assessed at both 5 and 10 min were significantly reduced in the vecuronium group (group B) (p < 0.05). We conclude that the addition of vecuronium at a dose of 0.5 mg to the standard local anaesthetic mixture improves the quality of globe and lid akinesia.
Keywords:Anaesthetic techniques, regional   peribulbar    Neuromuscular relaxants   vecuronium    Anaesthetics, local   lignocaine, bupivacaine
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