| 首发精神分裂症未治疗时间的变化及相关因素 |
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| 引用本文： | 首发精神分裂症未治疗时间的变化及相关因素. 首发精神分裂症未治疗时间的变化及相关因素[J]. 首都医科大学学报, 2016, 37(2): 168-171. DOI: 10.3969/j.issn.1006-7795.2016.02.012 |
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| 作者姓名： | 首发精神分裂症未治疗时间的变化及相关因素 |
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| 作者单位： | 1. 首都医科大学附属北京安定医院精神科 北京脑重大疾病研究院精神分裂症研究所 精神疾病诊断与治疗北京市重点实验室, 北京 100088;2. 北京中医药大学国医堂中医门诊部, 北京 100029 |
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| 基金项目： | 北京市自然科学基金(7152069), 北京市科委"首都临床特色应用研究"专项(Z151100004015061) |
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| 摘 要： | 目的 探索首发精神分裂症患者的精神病未治疗时间(duration of unmedicted psychosis, DUP)的变化规律及其相关因素。方法 对首都医科大学附属北京安定医院不同年份(1994、2004和2014年)首次发作的精神分裂症出院患者进行回顾性调查,描述DUP的变化。结果 不同年份在首都医科大学附属北京安定医院就诊的精神分裂症首次发作的患者中,2014年就诊患者的DUP显著小于1994年和2004年,但后两者之间差异无统计学意义(P>0.05)。2014年精神分裂症患者的DUP与其阳性与阴性症状量表(Positive and Negative Syndrome Scale,PANSS)减分率呈负相关。结论 精神分裂症患者从发病到开始治疗的疾病未治疗时间明显缩短,其中学生、未婚和高学历群体的比例呈增加趋势,显示了我国精神卫生事业的发展和进步。
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| 关 键 词： | 精神分裂症 精神病未治疗时间 阳性与阴性症状量表 |
| 收稿时间： | 2016-01-20 |
Changes of duration of untreated psychosis and its influential factors in patients with first-episode schizophrenia |
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| Liu Hui,Liu Shanshan,Jia Hongxiao. Changes of duration of untreated psychosis and its influential factors in patients with first-episode schizophrenia[J]. Journal of Capital Medical University, 2016, 37(2): 168-171. DOI: 10.3969/j.issn.1006-7795.2016.02.012 |
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| Authors: | Liu Hui Liu Shanshan Jia Hongxiao |
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| Affiliation: | 1. Center of Schizophrenia, Beijing Institute for Brain Disorders, Beijing Key Laboratory for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China;2. Chinese Medicine Outpatient Department of Guoyitang, Beijing University of Chinese Medicine, Beijing 100029, China |
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| Abstract: | Objective To explore the trends of change and related factors in duration of untreated psychosis (DUP) at first-episode of schizophrenia. Methods Retrospective investigation was employed on relieved patients with first-episode of schizophrenia in Beijing Anding Hospital, Capital Medical University from different years (1994, 2004 and 2014) to explore DUP changes.Results Statistical analyses showed that DUP in patients with first-episode of schizophrenia in 2014 was significantly lower than that in 1994 and 2004. However, there was no significant difference between the latter two groups. Besides, there was a negative correlation between DUP and reduced score rate of Positive and Negative Syndrome Scale (PANSS) in 2014. Conclusion The DUP was significantly shortened in patients with schizophrenia, in which the proportion of students, unmarried people and well educated population increased, showing the development and progress of mental health system in our country. |
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| Keywords: | schizophrenia duration of unmedicted psychosis Positive and Negative Syndrome Scale |
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