寻常性痤疮证候分布规律现代文献分析

目的 :探讨寻常性痤疮的证型及证素分布规律,为临床辨治本病提供依据。方法 :检索1983~2013年中国知网数据库(CNKI)中中医药治疗寻常性痤疮的临床随机对照试验和临床观察类文献,采用SPSS 16.0软件对寻常性痤疮的证型、证素分布进行统计分析。结果:纳入文献45篇,报道病例数6 211例。寻常性痤疮的临床常见证型包括肺经风热型、痰瘀互结型、脾胃湿热型,病性证素以火(热)、湿邪、瘀血、痰浊最为常见,病位证素以肺、胃、脾、冲脉、任脉最为常见。结论:目前寻常性痤疮研究存在文献质量不高(缺乏多中心、大样本的随机对照试验)、辨证分型尚无统一标准等问题,应根据痤疮证候分布规律对该病的临床辨证分型标准进行修订。

Analysis of Syndrome Distribution Rules of Ance Vulgaris in Modern Literature

Objective:To analyze the distribution rules of syndrome types and syndrome elements of ance vulgaris,so as to provide basis for clinical differentiation and treatment. Methods:Clinical observation literatures and randomized controlled trials about treatment of ance vulgaris by traditional Chinese medicine in China national knowledge infrastructure(CNKI) from 1983 to 2013 were retrieved. The syndrome types and syndrome elements of ance vulgaris were statistically analyzed by SPSS 16.0 software. Result:A total of 45 literatures met the inclusion criteria,involving 6 211 patients. Syndromes of ance vulgaris commonly seen in clinic are hot- wind in lung channel,accumulation of phlegm and blood stasis,and dampness- heat in spleen and stomach. The most common pathogenic elements were fire(heat),dampness,phlegm turbidity and blood stasis. The most common location elements were lung,stomach,spleen,thoroughfare vessel and conception vessel. Conclusions:The quality of the existing literatures on acne vulgaris research is not high(lacking of multicenter randomized controlled trials with large samples). There is no uniform standard for syndrome differentiation of ance vulgaris. The standard for clinical syndrome differentiation of ance vulgaris should be modified according to its syndrome distribution rules.