| HBV垂直传播与小儿乙型肝炎关系探讨 |
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| 引用本文： | 林国贤,赵汇川,杜庆岭,张光曙. HBV垂直传播与小儿乙型肝炎关系探讨[J]. 泰山医学院学报, 1993, 0(4) |
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| 作者姓名： | 林国贤 赵汇川 杜庆岭 张光曙 |
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| 作者单位： | 中国人民解放军88医院，中国人民解放军88医院，中国人民解放军88医院，中国人民解放军88医院 |
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| 摘 要： | 报道189例小儿乙肝,按直系亲属有无HBV感染分为阳性组和阴性组。阳性组74例(39.2％),母亲HBsAg阳性51例(68.9％),67.6％为慢性肝炎;阴性组115例(60.8％)父母HBsAg均阴性,15.7％为慢性肝炎。两组差异有非常显著意义(P<0.001)。两组在HBsAg阳性率、阴转率、抗—HBs阳性率、阴转率及HBeAg阳性率也有显著差异。73.4％小儿慢性乙肝与垂直传播有关。提示HBV垂直传播对小儿乙肝诊断和分型有重要意义。
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| 关 键 词： | 乙型肝炎 垂直传播 儿童 |
INVESTIGATION OF THE RELATIONSHIP BETWEEN HBV VERTICAL TRANSMISSION AND CHILDREN HEPATITIS B |
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| Lin Guoxian,Zhao Huichuan,Du Qingling,Zhang Guangshu. INVESTIGATION OF THE RELATIONSHIP BETWEEN HBV VERTICAL TRANSMISSION AND CHILDREN HEPATITIS B[J]. Journal of Taishan Medical College, 1993, 0(4) |
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| Authors: | Lin Guoxian Zhao Huichuan Du Qingling Zhang Guangshu |
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| Affiliation: | 88th Hospital of PLA |
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| Abstract: | 189 cases of children hepatitis B were reported. The patients were divided into positive and negative groups according to whether their family have HBV infection. There were 74 patients in positive group(39.2%), among them 67.7% was chronic; 51(68.9%) whose mother's HBsAg was positive. The other 115 patients were in negative group (60.8%), all their parents' HBsAg was negative, only 15.7% was chronic. There was significant difference between the two groups (P<0.001). There was also significant difference in HBsAg positive rate, turn-negative rate, anti-HBs positive rate, turn-positive rate and HBeAg positive rate. Vertical transmission happened in 73.4% of children chronic hepatitis B. There results suggested that HBV vertical transmission play an important role in the diagnosis and classification of children hepatitis B |
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| Keywords: | hepatitis B vertical transmission children |
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