踝臂指数评价2型糖尿病合并下肢外周动脉病患者疗效中的临床价值

目的 观察踝臂指数在2型糖尿病合并下肢外周动脉病患者治疗前后的变化,以探讨踝臂指数作为其疗效评价指标的可行性.方法 2型糖尿病合并下肢外周动脉病患者112例,分为单纯药物治疗组(62例)和介入治疗+药物治疗组(50例).详细记录每一患者的临床资料,包括年龄、性别、身高、体重、心率、血压、空腹血糖、餐后2 h血糖、糖化血红蛋白和血脂等结果.并分别于治疗前和治疗后1个月、3个月、6个月测踝臂指数.结果 2型糖尿病合并下肢外周动脉病患者治疗前踝臂指数小于0.90.介入治疗+药物治疗组治疗后1个月、3个月和6个月的踝臂指数与治疗前相比均有统计学意义(P<0.05),与单纯药物治疗组同期相比亦均有统计学意义(P<0.05).单纯药物治疗组治疗后1个月、3个月和6个月的踝臂指数与治疗前相比无明显变化(P>0.05).结论 踝臂指数在2型糖尿病合并下肢外周动脉病患者的治疗中起重要指导作用.介入治疗能够及早改善2型糖尿病合并下肢外周动脉病患者的血运,比单纯药物治疗疗效显著.

Clinical Application of Ankle-Brachial Index in the Treatment of Peripheral Arterial Disease in the Patients with Type 2 Diabetes Mellitus

Aim To investigate the clinical application of ankle-brachial index(ABI) in the treatment of peripheral arterial disease in the patients with type 2 diabetes mellitus. Methods 112 type 2 diabetic patients with peripheral arterial disease were randomly divided into drug treatment group(n=62) and interventional therapy and drug treatment group(n=50).All patients were checked for ABI by automatic analysis system of angiosclerosis. Results ABI was less than 0.90 in type 2 diabetic patients with peripheral arterial disease before therapy.ABI was increased in type 2 diabetic patients with peripheral arterial disease after interventional therapy and drug treatment(P<0.05).ABI was not increased in type 2 diabetic patients with peripheral arterial disease after drug treatment(P>0.05). Conclusion ABI is significant in type 2 diabetic patients with peripheral arterial disease who had taken the interventional therapy.