Oesophageal aspergillosis in a case of acute lymphoblastic leukaemia successfully treated with caspofungin alone due to liposomal amphotericin B induced severe hepatotoxicity |
| |
Authors: | Akyol Erikci A Ozyurt M Terekeci H Ozturk A Karabudak O Oncu K |
| |
Institution: | Department of Hematology;, Department of Microbiology;, Department of Internal Medicine;, Department of Dermatology;and Department of Gastroenterology, GATA Haydarpasa Training Hospital, Uskudar, Istanbul |
| |
Abstract: | Aspergillosis is one of the most common invasive fungal infections in immunocompromised patients. Sinonasal region and upper respiratory tract are commonly involved regions whereas oesophagus is seldom involved. We present an 18-year-old male with acute lymphoblastic leukaemia with aspergillosis of oesophagus which is a rare region of involvement. The diagnosis was confirmed by the examination of the cultures of endoscopic biopsy material. The patient was already receiving empirical liposomal amphotericin B, due to severe hepatotoxicity the therapy was switched to another antifungal (caspofungin). Here we report a case of successful treatment of invasive oesophageal aspergillosis by caspofungin. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|