无创双相正压通气对正常人血流动力学的影响

目的 :为了解无创双相正压通气 (BiPAP)对正常人血流动力学的影响。方法 :对2 2例正常自愿者进行研究 ,测定正常人在不同压力水平 (10 /4cmH2 O、 2 0 /10cmH2 O)的通气状态时及通过鼻罩或口鼻面罩通气时的心率、血压、心脏指数。结果 :1)虽然在某种通气方式时心率、血压的变化有统计差异 ,这种差异通过普通的临床监护设备并不能引起临床医师的注意 ;2 )正压通气使实验者的心脏指数下降 ,而且其下降程度与正压通气的压力正相关 ,心脏指数的下降主要由于心脏每搏指数的下降所致 ,心率的变化不是主要原因。结论 :临床工作中应综合评价BiPAP对患者的呼吸、循环功能的影响。

The effects of noninvasive bi-level positive airway pressure ventilation on normal human hemodynamics

Aim:This study was designed to understand the effects of BiPAP on human hemodynamics.Methods:22 young healthy volunteers were enrolled in this study.Their heart rates,blood pressures,cardiac indexes were measured when they were ventilated on positive pressure(10/4 cmH 2O,20/10 cmH 2O)via mask or nasal mask.Results:1)BiPAP ventilation caused little changes of heart rate and blood pressure.These changes are not prominent enough to be noticed by doctors with general monitor systems.2)BiPAP ventilation decreased cardiac index.The higher the pressure was used,the more the cardiac index decreased.Decreased cardiac index was attributed to decreased stroke volume.Conclusion:It is reasonable that the effects of BiPAP on patient hemodynamics should be evaluated comprehensively.