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| 谷胱甘肽滴眼液与乃奇安治疗老年性白内障的随机对照研究 | |
| 引用本文： | 李新芳,侯艳宁,吴静安,殷悦,晏晓明,韩秀娴,吴众,邹海兰,姜凌力,王磊峰,黄秋闽.谷胱甘肽滴眼液与乃奇安治疗老年性白内障的随机对照研究[J].解放军药学学报,2007,23(3):224-226. |
| 作者姓名： | 李新芳 侯艳宁 吴静安 殷悦 晏晓明 韩秀娴 吴众 邹海兰 姜凌力 王磊峰 黄秋闽 |
| 作者单位： | 1. 解放军白求恩国际和平医院,国家药品临床研究基地,河北,石家庄,050082 2. 北京大学第一医院,眼科,北京,100034 3. 河南眼科研究所,河南,郑州,450003 4. 北京军区总医院,眼科,北京,100005 |
| 摘 要： | 目的 评价国产谷胱甘肽滴眼液对老年性白内障的临床疗效及安全性.方法 175例白内障患者以3/2的比例随机分为两组,分别点国产谷胱甘肽滴眼液或乃安奇1～2滴,tid,疗程6个月.结果 国产谷胱甘肽滴眼液与乃安奇组的视力有明显的改善（P＜0.01）两组的总有效率为分别48.57%和44.28%（P＞0.05）.两组药物的不良反应轻微,发生率分别为19.05%、8.57%（P＞0.05）.结论 谷胱甘肽滴眼液是治疗老年性白内障安全、有效的药物. |
| 关 键 词： | 谷胱甘肽滴眼液 乃安奇 老年性白内障 |
| 文章编号： | 1008-9926（2007）03-0224-03 |
| 修稿时间： | 2005-01-132006-06-12 |
Randomized Controlled Study of The Anti-Cataract of Glutathione Ophthalmic Solution Compared with Neuthione in Patients with Senile Cataract |
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| LI Xin-Fang,HOU Yan-Ning,WU Jing-An,YIN Yue,YAN Xiao-Ming,HAN Xiu-Xian,WU Zhong,ZOU Hai-Lan,JIANG Lin-Li,WANG Lei-Feng,HUANG Qiu-Min.Randomized Controlled Study of The Anti-Cataract of Glutathione Ophthalmic Solution Compared with Neuthione in Patients with Senile Cataract[J].Pharmaceutical Journal of Chinese People's Liberation Army,2007,23(3):224-226. | |
| Authors: | LI Xin-Fang HOU Yan-Ning WU Jing-An YIN Yue YAN Xiao-Ming HAN Xiu-Xian WU Zhong ZOU Hai-Lan JIANG Lin-Li WANG Lei-Feng HUANG Qiu-Min |
| Institution: | 1.National Base for Drug Clinical Trial,Bethune International Peace Hospital of PLA,Shijiazhuang 050082;Hebei China;2.Department of Ophthalmology, First Hospital, Beijing University, Beijing 100034 China;3.Institute of Ophthalmology, Henan Province,Zhengzhou 450003 ; Henan China;4.Department of Ophthalmology, General Hospital of Beijing Command, Beijing 100005 China |
| Abstract: | Aim To evaluate the safety and efficacy of domestic glutathione ophthalmic solution in the clinical treatment of patients with senile cataract.Methods 175 patients with senile cataract were selected and at a ratio of three to two randomly divided into the glutathione ophthalmic solution group and the neuthione group.Each of them,respectively,received treatment of domestic glutathione ophthalmic solution and neuthioe by instilling 1 to 2 drops in the eye 3 times daily,for 6 months.Results The eyesight of the glutathione ophthalmic solution group and neuthione group was significantly improved(P< 0.01).The clinical efficacy rate of glutathione ophthalmic solution and neuthione was 48.57% and 44.28%(P>0.05),respectively.The adverse drug reactions of both groups were mild at 19.05%,8.57%,respectively.Conclusion This results suggest that glutathione ophthalmic solution is a safe and effective anti-cataract drug. |
| Keywords: | Glutathione ophthalmic solution Neuthione Senile cataract |
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