七叶皂苷钠治疗脑出血的临床观察

目的：探究七叶皂苷钠治疗脑出血的临床治疗效果。方法选取80例因脑出血入院治疗患者，按病床单双号分为联合组40例、单一组40例。单一组采用依达拉奉，联合组在此基础上加用七叶皂苷钠，观察两组患者脑出血、脑水肿情况，神经功能恢复情况，并根据综合指标判断疗效，统计用药期间不良反应情况。结果联合组总有效率高达95.0%，单一组为80.0%，单一组较联合组疗效差，差异有统计学意义（c2=4.114，P＜0.05）；未治疗时两组脑血肿、脑水肿、神经功能缺损程度比较差异无统计学意义，治疗后联合组神经功能、脑血肿、脑水肿分别为（4.74±2.67）、（12.62±4.27）、（9.15±3.15），单一组依次为（10.35±2.72）、（17.73±5.25）、（13.36±4.47）；联合组较单一组患者脑血肿、神经功能缺损明显好转，脑水肿明显控制，差异有统计学意义（t=9.309，t=4.776，t=4.869，P＜0.05）。结论临床对脑出血患者进行治疗时，为提高治疗效果加快患者恢复，改善患者神经功能缺损、促进血肿吸收、控制水肿扩散，可使用依达拉奉与七叶皂苷钠联合治疗。

Clinical observation of Sodium Aescinate in the treatment of cerebral hemorrhage

Objective To observe the clinical effect of Sodium Aescinate. Methods 80 patients with cerebral hemorrhage in our hospital were selected. The subjects were divided into two groups according to the odd or even number of hospital bed, 40 cases each group. The single group took the Edaravone Injection;on the basis, the combined group took the Sodium Aescinate Injection. The evaluation score of cerebral hemorrhage and cerebral edema, recovery of neurological function, clinical effect as well as adverse reactions for two groups were observed. Results The total effective rate of combined group (95.0%) was higher than single group (85.0%)(c2=5.556, P<0.05);before treatment, the evaluation score of cerebral hemorrhage, cerebral edema and neurological de-fects for two groups was not significantly different.After treatment, the evaluation score of cerebral hemorrhage, cerebral edema and neurological defects for combined group was (4.74±2.67), (12.62±4.27) and (9.15±3.15);the evaluation score for single group was (10.35±2.72), (17.73±5.25) and (13.36±4.47);the improvement of cerebral hemorrhage and neurological defects for combined group was better than single group; the cerebral edema was controlled(t1=9.309, t2=4.776, t3=4.869, P<0.05).Conclusion For patients with cerebral hemorrhage, the combined therapy of Edaravone and Sodium Aescinate can improve the recovery of neurological func-tion, control the cerebral edema and promote the patient’s fast recovery.