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脑缺血再灌注损伤机制研究进展
引用本文:刘磊,刘丽华,马玉奎. 脑缺血再灌注损伤机制研究进展[J]. 药学研究, 2016, 35(9): 542-544. DOI: 10.13506/j.cnki.jpr.2016.09.014
作者姓名:刘磊  刘丽华  马玉奎
作者单位:1. 山东宏济堂制药集团股份有限公司,山东 济南,262600;2. 山东省药学科学院,山东 济南,250100
摘    要:脑缺血再灌注损伤的发生和发展是一个复杂的病理生理过程,目前科研人员对其致病机制开展了广泛而深入的研究,提出了一系列学说,为解释脑缺血再灌注损伤的病理生理机制奠定了基础。本文综合国内外研究报道,对脑缺血再灌注损伤的病理生理机制进行综述,为其治疗提供参考。

关 键 词:脑缺血再灌注损伤  损伤机制  研究进展

Research progress on mechanisms of cerebral ischemia-reperfusion injury
LIU Lei,LIU Lihua and MA Yukui. Research progress on mechanisms of cerebral ischemia-reperfusion injury[J]. Journal of Pharmaceutical Research, 2016, 35(9): 542-544. DOI: 10.13506/j.cnki.jpr.2016.09.014
Authors:LIU Lei  LIU Lihua  MA Yukui
Affiliation:1.Shandong Hongjitang Pharmaceutical Group Co.,Ltd,Jinan 262600,China;2.Shandong Pharmaceutical Academy,Jinan 250100,China,1.Shandong Hongjitang Pharmaceutical Group Co.,Ltd,Jinan 262600,China;2.Shandong Pharmaceutical Academy,Jinan 250100,China and 1.Shandong Hongjitang Pharmaceutical Group Co.,Ltd,Jinan 262600,China;2.Shandong Pharmaceutical Academy,Jinan 250100,China
Abstract:The origin and development of the cerebral ischemia-reperfusion injury is a complex pathophysiological process.Scholars have made extensive and profound studies on mechanisms of cerebral ischemia-reperfusion injury and put forward a series of theories,which laid a foundation on the pathophysiology mechanism of cerebral ischemia-reperfusion in-jury.This article summarized progress on mechanisms of cerebral ischemia-reperfusion injury,in order to provide the refer-ences for the treatment of cerebral ischemia-reperfusion injury.
Keywords:Cerebral ischemia-reperfusion injury  Injury mechanism  Research progress
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