3D打印辅助上颌骨切除术后缺损重建

目的：探讨3D打印技术在上颌窦恶性肿瘤外科治疗中的可行性和应用效果。方法对5例因上颌窦恶性肿瘤行手术治疗的患者，根据术前CT扫描数据，应用3 D打印技术打印出患侧上颌窦的树脂模型，在此模型上对钛网进行塑形，制备出个性化钛网，将个性化钛网植入缺损区。通过临床和CT检查，评价其颌面部外形与功能。结果所有病例手术顺利，颌面部外形恢复良好，两侧对称，未见复视及眼球内陷，植入的钛网与缺损周边骨床贴合紧密。术后随访8～30个月，经临床和CT检查未见肿瘤复发。结论3 D打印技术在上颌窦恶性肿瘤的外科治疗中具有较好的可行性和可靠性，可提高上颌窦恶性肿瘤手术治疗的精确性及临床治疗效果。

Application of three-dimensional printing technique in assisting reconstruction after maxillectomy

Objective To investigate the application and clinical outcomes of 3-Dcomputer-assisted printing technique in the surgical treatment of malignant tumors of maxillary sinus.Methods Five patients suffering from malignant tumors of maxillary sinus received total maxillectomy were included in this study.Before operation,a three-dimensional indi-vidual stereo-maxillary model based on mirror images of the unaffected maxilla was obtained to fabricate an anatomically adapted titanium mesh using computer-assisted design and manufacturing.The individual titanium mesh was inserted in-to the maxillary after total maxillectomy.Facial appearance and function were evaluated by clinical and CT examina-tions.Results All patients were satisfied with their postoperative facial symmetry and did not develop diplopia or en-dophthalmos.During the operation procedure,the pre-bent titanium mesh did not require reshaping and pruning.The implanted titanium mesh fit bone bed surrounding the defect closely.Clinical and CT examinations showed recurrence in none during the follow-up of 8 to 30 months.Conclusion With good feasibility and reliability,3-dimensional printing technique is suitable for the surgical treatment of maxillary sinus malignant tumors,and can significantly improve the clinical outcome.