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肥胖与阻塞性睡眠呼吸暂停
引用本文:李延忠.肥胖与阻塞性睡眠呼吸暂停[J].山东大学耳鼻喉眼学报,2016,30(5):1-4.
作者姓名:李延忠
作者单位:山东大学 齐鲁医院耳鼻咽喉头颈外科/卫生部耳鼻喉科学重点实验室, 山东 济南 250012
摘    要:肥胖与OSA之间的关系是睡眠呼吸疾病领域一个新的热点,目前尚不清楚两者是因果关系还是伴随关系。肥胖胜过其他颅面畸形诱发阻塞性睡眠呼吸暂停(OSA),OSA 的频率与严重程度与体质量指数和肥胖相关,现就OSA与脂质代谢紊乱、脂肪肝、代谢性炎症、氧化应激四个方面的关系做一述评。

关 键 词:氧化应激  脂质代谢紊乱  睡眠呼吸暂停  阻塞性  脂肪肝  代谢性炎症  肥胖  
收稿时间:2016-09-19

Obesity and obstructive sleep apnea
LI Yanzhong.Obesity and obstructive sleep apnea[J].Journal of Otolaryngology and Ophthalmology of Shandong University,2016,30(5):1-4.
Authors:LI Yanzhong
Institution:Department of Otolaryngology &Head and Neck Surgery, Qilu Hospital of Shandong University / Key Laboratory of Otolaryngology of Health Ministry, Shandong University, Jinan 250012, Shandong, China
Abstract:The relationship between obesity and obstructive sleep apnea-hypopnea syndrome (OSAHS)has become a new hot spot in the research of sleep-disordered breathing.Whether there is a cause-and-effect or accompanying rela-tionship between them is not yet clear.Compared with craniofacial malformations,obesity is more likely to induce obstructive sleep apnea syndrome (OSA).The frequency and severity of OSA are related to BMI and obesity.This paper discusses the relationship from four aspects:lipid metabolism disorder,fatty liver,metabolic inflammation,and oxidative stress.
Keywords:Obstructive sleep apnea hypopnea syndrome  Obesity  Disorder of lipid metabolism  Fatty liver  Metabol-ic inflammation  Oxidative stress
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