北京中关村地区1984—2000年急性冠心病事件的流行病学研究

目的:了解中关村地区25～74岁人群1984—2000年急性冠心病事件发病率的分布特点、变化趋势及可能的影响因素。方法:依照北京MONICA研究中心的研究方案,1984—2000年在北京中关村地区对25～74岁近4万人群开展了心血管病危险因素及发病、死亡的监测工作。以中关村地区资料为依据,按年度、性别、年龄分别计算急性冠心病事件发病率的变化趋势。结果:1984—2000年中关村地区急性冠心病事件发病率呈轻度上升变化,但无统计学意义。男性合计发病率为128.5/10万,大于女性51.4/10万;其差异有统计学意义(P<0.01)。研究初期与研究末期相比,男性65～74岁组每10万人群发病率的绝对增加幅度最大,差率为307.8/10万,男性55～64岁组发病率相对增加幅度最大,差率为211%,均有统计学意义。医疗救助率为73.6%,高于北京市平均水平。发病集中在冬、春季,占总发病人数的58%。结论:中关村地区中老年男性急性冠心病事件发病率呈显著上升,应加强这一人群冠心病防治工作。

The epidemiological study of sacute coronary events in Zhongguancun area from 1984 to 2000

Objective:To investigate the distributions and trends of the incidence of acute coronary events in the population in Zhongguancun area of Beijing from 1984 to 2000,and to analyze the effect of medical treatment on coronary disease incidence and its trend.Method:A community-based prospective disease surveillance on cardiovascular disease was carried out in Zhongguancun area in Beijing from 1984 to 2000 using the methodology of the WHO-MONICA(multinational monitoring of the trends and determinants for cardiovascular disease)project.The monitoring area covered 40 thousand people aged 25-74.Crude and age-adjusted rates of acute coronary events were calculated by gender and age group.Annual percentage change was estimated by regression analysis.Result:There was no significant change in the incidence of acute coronary events in Zhongguancun area from 1984 to 2000.The incidence rate in men was significantly higher than that in women (128.5/ 100?000 in men and 51.4 / 100?000 in women).The maximum absolute increase in incidence ( 307.8 / 100?000 ) was seen in men aged 65-74 in the later stage of the study, compared with the earlier stage, and the maximum relative increase of 211% in incidence occurred in the age group of 55-64 in men.The rate of medical treatment was 73.6%,higher than the average level in Beijing.The events occurred mainly in winter or spring,accounting for 58% of the total.Conclusion:The incidence of acute coronary events is significantly increasing in older men in Zhongguancun area.The prevention of coronary heart disease in this population should be strengthened.