Rapid emergence of quinolone resistance in Campylobacter jejuni in patients treated with norfloxacin. |
| |
| Authors: | B Wretlind A Str?mberg L Ostlund E Sj?gren B Kaijser |
| |
| Affiliation: | Department of Clinical Bacteriology, Danderyd Hospital, Sweden. |
| |
| Abstract: | 15/60 subjects from one center, who all took part in a multicenter double-blind, placebo-controlled study to evaluate the effect of norfloxacin on acute enteritis, had norfloxacin sensitive strains of Campylobacter jejuni in pre-study stool specimens. Eight of the 15 subjects received active drug. In 3 of these 8, high-level quinolone resistant Campylobacter strains of the same serotype as in pre-treatment samples were isolated 4-90 days after the initiation of treatment. |
| |
| Keywords: | |
|
|
