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CD_4~+CD_(25)~+调节性T细胞与支气管哮喘
引用本文:陶松雪,潘家华. CD_4~+CD_(25)~+调节性T细胞与支气管哮喘[J]. 医学综述, 2007, 13(2): 127-129
作者姓名:陶松雪  潘家华
作者单位:安徽医科大学附属安徽省立医院儿科,合肥,230001
摘    要:人体内存在多种调节性T细胞,其中CD4+CD2+5调节性T细胞(CD4+CD2+5Treg)具有独特的作用方式和功能特征。CD4+CD2+5Treg在移植耐受、肿瘤免疫、过敏性疾病及微生物感染方面起着重要作用。支气管哮喘作为一种常见的慢性呼吸道疾病,其发病机制极为复杂,与免疫等多种因素有关。本文就CD4+CD2+5Treg的特性及在哮喘的发病和治疗方面研究进展作一综述。

关 键 词:CD4+CD25+调节性T细胞  支气管哮喘
文章编号:1006-2084(2007)02-0127-03
收稿时间:2006-05-21
修稿时间:2006-12-15

CD+4C+25 Regulatory T Cells and Asthma
TAO Song-xue,PAN Jia-hua. CD+4C+25 Regulatory T Cells and Asthma[J]. Medical Recapitulate, 2007, 13(2): 127-129
Authors:TAO Song-xue  PAN Jia-hua
Affiliation:Department of Pediatrics , Anhui Provincial Hospital , Anhui Medical College , Hefei 230001, China
Abstract:There are many kinds of regulatory T cells in human body,in which CD_4~ CD_(25)~ regulatory T cells have distinct mode of action and functional character.CD~ _4 CD~ _ 25 Treg are very important in transplantation tolerance,tumor immunity,anaphylactic disease and microbe infection.Asthma is a frequent chronic respiratory tract disease,whose pathogenesis is very complicated and related to multiple factors such as immunity.This review summarizes theCD_4~ CD_(25)~ Treg in its biological character and its mechanism of action in pathogenesis and therapy of asthma.
Keywords:CD_4~ CD_(25)~ regulatory T cells  Asthma
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