精神病医院医务人员乙型肝炎病毒感染临床分析

目的探讨精神病医院医务人员乙型肝炎病毒(HBV)感染状况,为医院进一步预防医患间HBV交叉感染提供依据。方法对全院281名医务人员用ELISA法检测乙肝表面抗原(HBsAg)乙肝表面抗体(抗-HBs)乙肝e抗原(HBeAg)乙肝e抗体(抗-HBe)乙肝核心抗体(抗-HBc)五项血清标志物。结果精神病医院医务人员HBV感染率53.38%,其中HBsAg阳性率11.39%,男性医务人员HBsAg阳性率10.92%,女性医务人员HBsAg阳性率11.73%,两组间无显著差异(P>0.01);临床医务人员HBsAg阳性率15.17%,非临床医务人员的HBsAg阳性率4.85%,两组间有显著性差异(P<0.01)且临床医务人员的HBsAg阳性率高于全国平均HBsAg阳性率,五项血清标志物全部阴性者占46.62%,主动注射乙肝疫苗获得免疫者(包括部份被动免疫者)占31.67%。结论积极改善精神病患者居住条件,加强预防与及时治疗HBV感染的精神病患者,大力宣传和提高精神病医院医务人员对传染病的防范意识并积极采取相应的防护措施预防HBV在医患间和患者之间传播感染,是当前精神病医院感染管理工作的一项重要内容,也是医院医疗质量管理的一项重要内容。

Investigation and analysis of the hepatitis B virus infection in the medical staff of a psychiatric hospital

Objective To study the medical personnel of asylum HBV infection condition,to provide basis to prevent cross infection in medical affairs.Methods HbsAg,HBsAb,HBcAb,HBeAg and HBeAb were examined in 281 medical personnels of whole hospital using the ELISA method.Results HBV infection rate of medical personnel in the asylum was 53.38%,and the positive rate of HBsAg was 11.39%,including 10.92% of the males and 11.73% of the females.There was no significant difference between them（P〈0.01）.The HBsAg positive rate was 15.17% in clinical medical personnel and 4.85% in the none clinical medical personnel,it showed a significant difference（P〈0.01）.The HbsAg positive rate in clinical medical personnel was higher than the average.46.62% of the staff had all of these five serums marks negative,while 31.67% of them took the vaccine initiatively.Conclusion It is very important to improve the living condition of patients with mental diseases.It could mostly prevent the infectious diseases if we strengthen the HBV prevention management.It is an important content of the infection management work in current mental illness hospital,and also an important content of the hospital medical treatment quantity management.