大肠灌洗联合康复新液灌肠治疗溃疡性结肠炎的临床疗效观察

目的观察用结肠灌注治疗机灌洗后联合康复新液保留灌肠治疗溃疡性结肠炎的疗效。方法选择2011年6月～2012年6月收治的溃疡性结肠炎患者112例,随机分为对照组和观察组各56例。对照组患者给予甲硝唑联合地塞米松灌肠治疗。观察组患者先采用结肠灌注透析治疗机进行治疗,再给予康复新液100ml加入地塞米松10mg,加温至38℃左右,灌肠治疗。均为1次/d,10d为一个疗程,隔二周再行第2个疗程。结果经过2个疗程治疗后,对照组患者显效9例,有效34例,无效13例,总有效率76.79%。观察组患者显效12例,有效39例,无效5例,总有效率91.07%。两组总有效率比较,观察组明显高于对照组,差异有统计学意义(P<0.05)。结论采用结肠灌注治疗机灌洗后联合康复新液保留灌肠治疗溃疡性结肠炎可以获得较满意的疗效,值得临床推广。

A clinical study on the combined treatment of enema and New Liquid of Recovery in colon for Ulcerative colitis

Objective To study the clinical effect of combined treatment of enema and New Liquid of Recovery on Ulcerative colitis,and provide data for Ulcerative colitis therapy.Methods 112 Ulcerative colitis（UC） patients who hospitalized in Chongqing Qianjiang national hospital from June 2011 to June 2012 were selected as the objectives.They were randomly divided into observation group（n=56） and control group（n=56）.The control group was treated with combined enemas of metronidazole and dexamethasone.The observation group was treated with the colon dialysis machine（CTJ-A） firstly,then clystered 100ml New Liquid of Recovery with 10mg dexamethasone dissolved（heated to 38℃）.Both groups were treated once a day for 10 continuous days,which regarded as a treatment course.After two weeks,the other 10-days treatment course was performed.Results After two courses of treatment,9 cases in the control group were obviously improved,34 cases were effective,and 13 cases were invalid,which effective rate is 76.79% in the control group.In the observation group,12 cases were obvious effective,39 cases were effective,and only 5 cases were invalid,which effective rate is 91.07%in the control group.So the effective rate of the observation group is higher significantly than that of the control group（P〈0.05）.Conclusion The combined enemas treatment with both CTJ-A and New Liquid of Recovery for Ulcerative colitis is more effective.So this combination treatment method is worthwhile for spreading in clinical practice.