| 甲醛对大鼠的氧化性损伤 |
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| 引用本文： | 崔香丽,雷玲.甲醛对大鼠的氧化性损伤[J].中国公共卫生学报,1995,14(5):287-289. |
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| 作者姓名： | 崔香丽 雷玲 |
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| 作者单位： | 山西医学院毒化教研组，山西医学院卫生毒理教研组 |
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| 摘 要： | 大鼠吸入不同剂量甲醛１０天，其血、肺、肝、肾、睾丸、脑和眼球脂质过氧化物（ＬＰＯ）均有增加趋势．肝和睾丸ＬＰＯ增加有统计学意义。肾ＧＳＨＰＸ活性随甲醛浓度加大而显著升高。肝和睾丸组织ＬＰＯ／ＧＳＨＰＸ比值显著升高。表明甲醛吸入可造成大鼠肝脏和睾丸的脂质过氧化损伤，并使它们的抗氧化能力降低。
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| 关 键 词： | 甲醛，脂质过氧化，谷胱甘肽过氧化物酶，肝，睾丸，脏器 |
Formaldehyde Inhalation Led to Lipid Perokidation of Rat Organs |
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| Authors: | Cui Xiangli |
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| Institution: | Dept. of Toxical Chemistry Shanxi Medical College Taiyuan 030001 |
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| Abstract: | Rats inhaled formaldehyde for 10 days. The results showed a tendency of increases of lipid peroxidation (LPO) in rat. serum, lung, liver. kidney. testis, brain and eye samples. LPO increases in rat liver and tsetises significantly. The ratio of LPO/GSHPX increased significantly in rat liver and taetic when formaldehyde concentration is above 42mg/m3. The above results proved that formaldehyde inhalation can led to lipid peroxidation in rat liver and testises. |
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| Keywords: | Formaldehyde Lipid peroxidation Glutathione Peroxidase Liver Testis Organs |
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